DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14696 and ROD1

DIOPT Version :9

Sequence 1:	NP_650035.1	Gene:	CG14696 / 41317	FlyBaseID:	FBgn0037853	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_014661.1	Gene:	ROD1 / 854183	SGDID:	S000005544	Length:	837	Species:	Saccharomyces cerevisiae

Alignment Length:	532	Identity:	94/532 - (17%)
Similarity:	178/532 - (33%)	Gaps:	159/532 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 LISGTAELITERPKTIRSIFI---------------TINGYGETRWQESEERV------------ 59
            |:|||..|....|..|:|:.:               |::| ...|:.:.|..:
Yeast    40 LLSGTIVLSITEPIQIKSLALRLFGRLRLNIPTVLQTVHG-PHKRYSKFERNIYSHFWDDFNIKS 103

  Fly    60 --------GEDGKTTKSLVTHT------------TTEVYYSTDQPVYGQAGGSQ--LELPTGKYV 102
                    ..:||.|.|..:.|            :|....|::    ||...|:  ..|..|.|.
Yeast   104 YFQNLYDNHNNGKITISSKSSTNLAALPKRKRALSTASLISSN----GQTSASKNYHTLVKGNYE 164

  Fly   103 FPFRATIPPNAPTSFNG-AHGQIKHEVTLTIDRAVRYNNTFKQCFTVILPHDLNRRLEYKEPLQR 166
            |||.|.||.:...|..| .:..:.:.:..||:|..:.:...|:...||    ....::..|..:.
Yeast   165 FPFSAIIPGSLVESVEGLPNAAVTYALEATIERPKQPDLICKKHLRVI----RTLAIDAVELSET 225

  Fly   167 LESKSFWWGSIFGAHKPMIMDVSTSYSAYVPGQKIHFH-------LVLDNQSDVQCMDVKVRLIK 224
            :...:.|         |..:|    |:..:|.:.|...       |::.....::...|::.|::
Yeast   226 VSVDNSW---------PEKVD----YTISIPTKAIAIGSSTMINILIVPILKGLKLGPVRISLVE 277

  Fly   225 NVSYRANSSGA-KEQLKVTESRVAD--KHCGEVLK-------------------HNKAKFDEFLT 267
            |..|..:..|. .::..|.:.::.|  ||..::.|                   .:|.:....|.
Yeast   278 NSQYCGSYGGVINQERMVAKLKLKDPLKHVAQIKKKRSLNEAADEGVDTDTGEFQDKWEVRALLN 342

  Fly   268 VPPTTPSTQSEKD-----PIRVSYTLRFIAKTFKLHGG-GDLVMDFPITIGTVPLLGSADDKGPG 326
            :|.:.  |:..:|     .|:|.:.::|........|. .:|....|:.:...|.:       |.
Yeast   343 IPASL--TKCSQDCRILSNIKVRHKIKFTISLLNPDGHISELRAALPVQLFISPFV-------PV 398

  Fly   327 AEKSQPSGASHPGSPNFQEDVSDEQFESNTFKPRYPVYPFDGKPGTNGSNGAANFPSLYPKAEE- 390
            ..|:              .||.:...:  ||.|.|.|        |:..:.:.:..:....:||
Yeast   399 NVKT--------------SDVIERTLK--TFGPSYQV--------TSQHDNSFSSKNFVDDSEED 439

  Fly   391 ---AHPATPVKFTPNPVSPAAQKSPPYTTNTPVASPPGGNFEVLGFSIPPDY------------- 439
               ...|:.::.:..|...:.......:|:.. |:.......|....:||:|
Yeast   440 VIFQRSASALQLSSMPTIVSGSTLNINSTDAE-ATAVADTTMVTSLMVPPNYGNHVYDRVYGEVT 503

  Fly   440 -KPTPSAPAASS 450
             :...||.|:||
Yeast   504 NEDETSASASSS 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14696	NP_650035.1	Arrestin_N	5..155	CDD:278754	39/182 (21%)
CG14696	NP_650035.1	Arrestin_C	182..313	CDD:280848	27/165 (16%)
ROD1	NP_014661.1	Arrestin_N	<157..215	CDD:419887	17/61 (28%)
ROD1	NP_014661.1	Arrestin_C	232..395	CDD:214976	28/177 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343411
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11188
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840