Protein Alignment CG14696 and ALY2

DIOPT Version :10

• Sequence 1: NP_650035.1
• Gene: CG14696 / 41317
• FlyBaseID: FBgn0037853
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_012451.1
• Gene: ALY2 / 853361
• SGDID: S000003620
• Length: 1046
• Species: Saccharomyces cerevisiae
• Alignment Length: 578
• Identity: 113/578 - (19%)
• Similarity: 201/578 - (34%)
• Gaps: 166/578 - (28%)

  Fly     6 NFVFDSNPLGLYQAGQLISGTAELITERPKTIRSI-FITINGYG-------ETRWQESEER---- 58
            ||:...:...||:.   :|.. |.||.|..:|..: .:.::..|       ..:.:||.:|
Yeast   140 NFLTKESGASLYRT---LSDN-ETITSRKNSISGLSSLNLSPLGAPGNSSVNVKDRESRQRSRSS 200

  Fly    59 --VGEDG------------KTTKSLVTH-----TTTEVYYS------------------------ 80
              ...:|            :.|...|:|     |||.::..
Yeast   201 SVTSSNGPSRNLSPINLLKRATSPSVSHHNYKPTTTSIFSDLLNNTFTHNDAASHHGHHIPTSSN 265

  Fly    81 ----TDQPVYGQAGGSQLELPTGKYVFPFRATIPPNAPTSFNGAHGQIKHEVTLTIDR--AVRYN 139
                |.......:||.......|.|::.|...||...|.|.....|.:::.:..:|:|  |.:.|
Yeast   266 HLAMTSNNFTSGSGGEFFVFQPGDYIYAFEELIPQAYPESIKADFGFVEYFLFASIERPGAFKSN 330

  Fly   140 NTFKQCFTVILPHDLNRRLEYKEPL---QRLESKSFWWGSIFGAHKPMIMDVSTSYS-AYVPGQK 200
            .:.:|...::.....| .:|..||:   :..|::.::  .|..|.|.:|:|.....: .:.|..|
Yeast   331 ISARQVVNIVRTQAHN-SVEESEPIIISRDWENQLYY--DIVIASKDIILDAFLPITFKFAPLDK 392

  Fly   201 IHFH---LVLDNQSDVQCMDVKVRLIK----------------NVSYRANSSGAKEQLKVTESRV 246
            :..|   :.:....:..|.:.||..::                |:...||.|.||....:.:
Yeast   393 VTLHRIRIYVTETMEYYCREKKVHRMEPTKKFLLTEQKGPKLPNLPNDANLSKAKNMGNLLQ--- 454

  Fly   247 ADKHCGEVLKHNK---------AKFDEFLTVPPTTPSTQSEKDP-IRVSYTLRFIAKTFKLHGGG 301
             |...|:::  ||         ::|:....:.|.|.....:.:. |::...|..:....:.|  .
Yeast   455 -DPKNGDLV--NKEYEYQIFIPSRFNNHQQLHPDTSYENIKANHWIKICLRLSRVVDNKRKH--Y 514

  Fly   302 DLVMDFPITIGTVPLLGSADDKGPGAEKSQPSGASHPGSPNFQEDV----------SDEQF---- 352
            ::.:|.||.:  :..|.|      .|....||...||.|  |.::.          ||:..
Yeast   515 EISIDSPIHV--LHRLCS------HANTLLPSYDGHPAS--FPKETDSSISSILESSDDNINLYH 569

  Fly   353 ESNTFKPRY---------PVYPFD----GKPGTNGSNGAANFPSLYPKAEEAHPA-----TPVKF 399
            .||.|.|:.         .|.|.|    ..|.|:.:..:..|    .:..::||:     ...|.
Yeast   570 NSNIFFPKEVLSSPVLSPNVQPLDILIPHLPSTSLTRNSRQF----NRNSKSHPSDNTIFNSAKL 630

  Fly   400 TPNPVSPAAQK----SPPYTTNTPVASPPGGNFEVLGFSIPPDYKPTPS--APAASST 451
            ..|...|.:.:    ||.....:|:.||. .|.||    .|||:..:..  :.|||.|
Yeast   631 KSNIYQPESLQRELASPQAIPLSPITSPM-SNMEV----PPPDFDFSSDFISDAASGT 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14696	NP_650035.1	Arrestin_N	5..155	CDD:425619	37/209 (18%)
		Arrestin_C	182..316	CDD:460676	28/163 (17%)
		PHA03247	<313..450	CDD:223021	39/174 (22%)
ALY2	NP_012451.1	Arrestin_N	<254..341	CDD:451447	16/86 (19%)
		Arrestin_C	360..526	CDD:214976	31/177 (18%)
		PTZ00112	620..>924	CDD:240274	18/69 (26%)