Protein Alignment CG14696 and ROG3

DIOPT Version :9

• Sequence 1: NP_650035.1
• Gene: CG14696 / 41317
• FlyBaseID: FBgn0037853
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_116677.3
• Gene: ROG3 / 850578
• SGDID: S000001918
• Length: 733
• Species: Saccharomyces cerevisiae
• Alignment Length: 640
• Identity: 104/640 - (16%)
• Similarity: 180/640 - (28%)
• Gaps: 240/640 - (37%)

  Fly    22 LISGTAELITERPKTIRSIFITING----------------------------YGETRWQESEER 58
            |:||...|....|..|:||.:.:.|                            |.:..:..:.:.
Yeast    41 LLSGCIVLSINEPMQIKSISLRLYGKIQIDVPLERPQDASSSSLSSSPPKIRKYNKVFYNYAWDN 105

  Fly    59 V-------------GEDGKTTKSLVTHTTTEVYYSTD-QPVYGQAGGSQLELPTGKYVFPFRATI 109
            |             |..|.::.|.:..|......::. :.:.|.:..|...|..|.|.|||.|.:
Yeast   106 VNLKEYLSGLRGQSGLAGSSSSSNILGTRQRAQSTSSLKSLKGSSSPSSCTLDKGNYDFPFSAIL 170

  Fly   110 PPNAPTSFNGAHGQIKHEVTLTIDRAVRYNNTFKQCF-TVILPHDLNRRLEYKEPLQRLESKSFW 173
            |.:.|.|.                      .:...|| |..:...:.|...|.:.:.|...:
Yeast   171 PGSLPESV----------------------ESLPNCFVTYSMESVIERSKNYSDLICRKNIR--- 210

  Fly   174 WGSIFGAHKPMIMDVS------------TSYSAYVPGQKIHFH-------LVLDNQSDVQCMDVK 219
               :.....|..:::|            ..||..||.:.:...       .::.....::...:|
Yeast   211 ---VLRTISPAAVELSETVCVDNSWPDKVDYSISVPNKAVAIGSATPINISIVPLSKGLKLGSIK 272

  Fly   220 VRLIKNVSY-RANSSGAKEQLKVTESRVAD---KHCGEVLKH----------------NKAKFDE 264
            |.|.:|..| ........|..:|||..:.|   :..||...:                :|.:.|.
Yeast   273 VVLFENYQYCDPFPPVISENRQVTELNLEDPLNESSGEFNGNGCFVNNPFFQPDHSFQDKWEIDT 337

  Fly   265 FLTVPPTTPSTQSEKD---PIRVSYTLRFIAKTFKLHG-GGDLVMDFPITIGTVPL-------LG 318
            .|.:|.:..:...:.|   .|:|.:.|:|........| ..:|....||.:...|.       |.
Yeast   338 ILQIPNSLSNCVQDCDVRSNIKVRHKLKFFIILINPDGHKSELRASLPIQLFISPFVALSIKPLS 402

  Fly   319 SAD-----------DKGPGAEKSQP-------------------SGASHP------GSPNFQEDV 347
            |::           |:....|:.:.                   ||.|.|      ..||::..|
Yeast   403 SSNLYSLFSTTNQKDENSSQEEEEEYLFSRSASVTGLELLADMRSGGSVPTISDLMTPPNYEMHV 467

  Fly   348 SDE----QFESNTFKPRYPVYPFDGKPGT-----------------------------NGSNGAA 379
            .|.    .|.....:......|...:..|                             :.|:.||
Yeast   468 YDRLYSGSFTRTAVETSGTCTPLGSECSTVEDQQQDLEDLRIRLTKIRNQRDNLGLPPSASSAAA 532

  Fly   380 --------NFPSLYPKAEEAHPATPVKFTPN------------PVSPAAQKSPPYTTNTPVASPP 424
                    |.|:.....|...|.:.:  .||            ||..:...:|..:.:..:..|.
Yeast   533 SRSLSPLLNVPAPEDGTERILPQSAL--GPNSGSVPGVHSNVSPVLLSRSPAPSVSAHEVLPVPS 595

  Fly   425 GGN------------------FEVLGFSIPPDY----------KPTPSAPAASST 451
            |.|                  ::::|..:||.|          ||:......|||
Yeast   596 GLNYPETQNLNKVPSYGKAMKYDIIGEDLPPSYPCAIQNVQPRKPSRVHSRNSST 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14696	NP_650035.1	Arrestin_N	5..155	CDD:278754	30/175 (17%)
		Arrestin_C	182..313	CDD:280848	31/173 (18%)
ROG3	NP_116677.3	Arrestin_N	<156..215	CDD:419887	16/86 (19%)
		Arrestin_C	232..393	CDD:214976	29/160 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343410
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11188
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930