DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14696 and CG18746

DIOPT Version :9

Sequence 1:	NP_650035.1	Gene:	CG14696 / 41317	FlyBaseID:	FBgn0037853	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_652649.1	Gene:	CG18746 / 59142	FlyBaseID:	FBgn0042103	Length:	438	Species:	Drosophila melanogaster

Alignment Length:	423	Identity:	115/423 - (27%)
Similarity:	183/423 - (43%)	Gaps:	70/423 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 FDSNPLGLYQAGQLISGTAELITERPKTIRSIFITINGYGETRWQESEERVGE--DGKTTKSLVT 71
            |.:|..|::.|||||||...:.||:.|:::::.:.|.||.||.|.::|....:  :|::....|.
  Fly     8 FCNNSQGIFYAGQLISGQVVIKTEKEKSVKAVILNIKGYAETHWADTEHDPDDQSNGESFNGHVD 72

  Fly    72 HTTTEVYYSTDQPVYGQAGGSQLELPTGKYVFPFRATIPPNAPTSFNGAHGQIKHEVTLTIDRAV 136
            :..|..|      ::|.:...::.:..|...:.|...:|...|:||.|..|:|::.|.:...|..
  Fly    73 YLATRAY------LHGSSSSIEVLIEPGTSSYRFACQLPITCPSSFEGTLGRIRYLVNVRFVRPW 131

  Fly   137 RYNNTFKQCFTVILPHDLN-RRLEYKEPLQRLESKSFWWGSIFGAH-KPMIMDVSTSYSAYVPGQ 199
            :::..|.:|||||...||| ..|..:.|.|....::|   ..|... .|:.|.:|...|.:||||
  Fly   132 KFDLNFNRCFTVIKVMDLNSESLMLRVPSQVESQRTF---CCFPCRSSPLSMRLSVPQSGFVPGQ 193

  Fly   200 KIHFHLVLDNQSDVQCMDVKVRLIKNVSYRANSSGA---KEQLKVTESRVADKHCGEVLKHNKAK 261
            .:...:::.|.|.|...|:.|:|...|.|.:....|   |::.::..     |..|.|....:.:
  Fly   194 IVPVEVMVSNDSGVAVEDITVKLTMVVIYYSQPPSADTNKDRFEMVL-----KTGGGVSTKCRQQ 253

  Fly   262 FDEFLTVPPTTPSTQSEKDPIRVSYTLRFIAKTFKLHGGGDLVMDFPITIGTVPLLGSADDKGPG 326
            |...|.||||.|:..:....|::.|.:...|:....|||..|.|  |||||:|||
  Fly   254 FTFDLKVPPTPPTCFNLCSIIQIGYQVEAEARVKGCHGGQSLHM--PITIGSVPL---------- 306

  Fly   327 AEKSQPSGASHPGSPNFQEDVSDEQFESNTFKPRYPVYPFDGKP----GT--NGS-----NGAAN 380
                                ....|.|..|:....|....|.|.    |:  ||.     |..|.
  Fly   307 --------------------TKQLQKEPRTWGEVLPPQQLDAKALILIGSEQNGEALGSPNPWAA 351

  Fly   381 FPSLYPK--AEEAHPATPVKFTPNPVSPAAQKS 411
            .||:.|.  ||..|    :...|:..|.:.:||
  Fly   352 DPSIAPPSYAEAKH----ISPDPHKFSKSKKKS 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14696	NP_650035.1	Arrestin_N	5..155	CDD:278754	43/147 (29%)
CG14696	NP_650035.1	Arrestin_C	182..313	CDD:280848	40/133 (30%)
CG18746	NP_652649.1	Arrestin_N	4..150	CDD:278754	43/147 (29%)
CG18746	NP_652649.1	Arrestin_C	174..306	CDD:214976	42/138 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464060
Domainoid	1	1.000	94	1.000	Domainoid score	I7396
eggNOG	1	0.900	-	-		E1_KOG3780
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	43	1.000	Inparanoid score	I2088
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110793at6960
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	1	1.000	-	-		otm24709
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11188
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X122
	10	9.900