DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14696 and CG3014

DIOPT Version :9

Sequence 1:	NP_650035.1	Gene:	CG14696 / 41317	FlyBaseID:	FBgn0037853	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001138022.2	Gene:	CG3014 / 40922	FlyBaseID:	FBgn0037519	Length:	488	Species:	Drosophila melanogaster

Alignment Length:	422	Identity:	97/422 - (22%)
Similarity:	175/422 - (41%)	Gaps:	86/422 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 NPLGLYQAGQLISGTAELITERPKTIRSIFITINGYGETRWQESEERVGEDGKTTKSLVT----- 71
            ||  :|.:|:.|||...|.|::.|.:.::::|:.|..:.:|..|       ||:..:..:
  Fly    13 NP--VYNSGEYISGRILLRTDKVKRVNAVYVTLEGEAKVQWSMS-------GKSETANYSGHQQY 68

  Fly    72 -HTTTEVYYSTDQPVYGQAGGSQLELPTGKYVFPFRATIPPNAPTSFNGAHGQIKHEVTLTIDRA 135
             |:.|.|:.:|             ....|.:|:.....|||:.|::..|.:|.|.:.::||||:.
  Fly    69 LHSRTNVFDNT-------------LFRAGVHVYVLTLRIPPDCPSTCKGPYGYIAYTISLTIDKP 120

  Fly   136 VRYNNTFKQCFTVILPHDLNRRLEYKEPLQRLESKSF-WWGSIFGAHKPMIMDVSTSYSAYVPGQ 199
            ..::..|::...|:...|||...|:..|::....|.. .|..|.|   |:...::...|.:.|.|
  Fly   121 WGFDEVFRKPIIVVQTLDLNYNAEFSLPVKDENLKYLCHWPCISG---PICSTLTLPASGFTPLQ 182

  Fly   200 KIHFHLVLDNQS---DVQCMDVKVRL---------IKNVSYRANSSGAKEQLKVTESRVADKHCG 252
            ::.:.|.:||||   |:..::|.::.         :|...|...         :.:..::|:
  Fly   183 EVPYRLEVDNQSPHYDIIGVEVSIKQHFVFLSRKPVKRNFYSKT---------LVKELISDR--- 235

  Fly   253 EVLKHNKAKFDEFLTVPPTTP-STQSEKDPIRVSYTLRFIAKTFKLHGGGDLVMDFPITIGTVPL 316
             .|:.:|.:::..:.||..|| ||.:....:.:.|||:...||...|...||  ..||.:||..|
  Fly   236 -TLRLSKRQYESSICVPMDTPRSTLNPNYIVFLHYTLQVKLKTGYFHYDTDL--SVPIIVGTTSL 297

  Fly   317 LGSADD--------KGPGAEKSQPSGASHPGSPNFQED---------------VSDEQFES--NT 356
            ....|.        :.|..|:.:......|..|..:||               :.|::..|  :.
  Fly   298 QHLRDSVHTQQPVRRTPTPERQRLIERVTPRPPTVEEDSAGEADPATDEPHRVIEDDEPPSYDSC 362

  Fly   357 FKPRYPVYPFDGKPGTNGSNGAANFPSLY-PK 387
            ..|.:......|...|.|||.|.....:: ||
  Fly   363 LPPSFSFATLAGSQQTLGSNAAVVLQRIHLPK 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14696	NP_650035.1	Arrestin_N	5..155	CDD:278754	36/148 (24%)
CG14696	NP_650035.1	Arrestin_C	182..313	CDD:280848	32/143 (22%)
CG3014	NP_001138022.2	Arrestin_N	5..140	CDD:304627	36/148 (24%)
CG3014	NP_001138022.2	Arrestin_C	164..294	CDD:280848	33/147 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464051
Domainoid	1	1.000	63	1.000	Domainoid score	I10233
eggNOG	1	0.900	-	-		E1_KOG3780
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	43	1.000	Inparanoid score	I2088
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110793at6960
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11188
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X122
	9	8.900