DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14696 and CG2641

DIOPT Version :9

Sequence 1:	NP_650035.1	Gene:	CG14696 / 41317	FlyBaseID:	FBgn0037853	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_649737.1	Gene:	CG2641 / 40921	FlyBaseID:	FBgn0037518	Length:	429	Species:	Drosophila melanogaster

Alignment Length:	493	Identity:	141/493 - (28%)
Similarity:	211/493 - (42%)	Gaps:	105/493 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSSKVNFVFDSNPLGLYQAGQLISGTAELITERPKTIRSIFITINGYGETRWQESEERVGEDGKT 65
            |.|..:|..|... .:|.:|:.::|.|.|.|...|::..::|...|..:.||.|...|. ..|||
  Fly     1 MPSSCSFELDRRE-PIYYSGETVNGRAILTTTSEKSVNEVYILFEGEAKVRWDERRTRT-RGGKT 63

  Fly    66 TKSLVTHTTTEVYYSTDQPVYGQAGGSQLELPTGKYVFPFRATIPPNAPTSFNGAHGQIKHEVTL 130
            ..........:.|..|...|:|..     .||.|.:.:.|...:|...|:|....:|:|.:||::
  Fly    64 EHYTEYFRGKQQYLYTRTSVFGSG-----NLPPGTHTYNFCIPLPLECPSSVVAQYGKIFYEVSV 123

  Fly   131 TIDRAVRYNNTFKQCFTVILPHDLNRRLEYKEPLQRLESKSF-WWGSIFGAHKPMIMDVSTSYSA 194
            .|||..|:||.|||..|||..::||...:...||.|.:.|.| .|....|   |::..::..:..
  Fly   124 VIDRQWRFNNVFKQPLTVIQTYNLNMSPQLLMPLVREDIKHFCCWPCSSG---PVLSTLTIPFGG 185

  Fly   195 YVPGQKIHFHLVLDNQS---DVQCMDVKVRLIKNVSYRANSSGAKEQLKVTESRVADKHCGE--V 254
            |.|||||.|.|.:||||   |:..:::|::.|  ..::|.:...|.:.|   ....:|.|.:  |
  Fly   186 YAPGQKIRFTLEIDNQSSGYDLNGIELKLKQI--YKFQAQTPHHKTREK---EHSLNKSCQQERV 245

  Fly   255 LKHNKAKFDEFLTVPPTTPSTQSEKDPIRVSYTLRFIAKTFKLHGGGDLVMDFPITIGTVPLLGS 319
            |:.:|.|.:..|.:|...||:::| ..|.|||.:.....|...|...|  .:.||.|||:||:.|
  Fly   246 LRLSKKKIEGTLAIPAVPPSSRTE-GIISVSYQVILTISTGDCHVDSD--FEVPIVIGTIPLIQS 307

  Fly   320 ADDKGPGAE-----KSQPSGASH--PGS------PNFQE---------DV-SDEQFESNTFKPRY 361
            |::....|:     ...|:||:.  |.|      |.|:|         |: .||...::.|.|||
  Fly   308 AENPASAAQWIPETPDTPAGAAADLPPSYDKCKPPTFEEATNFGERFIDIDQDEHNRTDDFIPRY 372

  Fly   362 PVYPFDGKPGTNGSNGAANFPSLYPKAEEAHPATPVKFTPNPVSPAAQKSPP--YTTNTPVASPP 424
            |:|              .||                      ..|:|...||  :.||.||
  Fly   373 PMY--------------TNF----------------------AMPSAPPQPPEEFATNQPV---- 397

  Fly   425 GGNFEVLGFSIPPDYKPTPSAPAASS------TGGIGW 456
                .||  |:|.|    |:||....      |...||
  Fly   398 ----PVL--SLPHD----PTAPLVGQNNTDRPTQSYGW 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14696	NP_650035.1	Arrestin_N	5..155	CDD:278754	45/149 (30%)
CG14696	NP_650035.1	Arrestin_C	182..313	CDD:280848	40/135 (30%)
CG2641	NP_649737.1	Arrestin_N	5..148	CDD:278754	45/149 (30%)
CG2641	NP_649737.1	Arrestin_C	171..301	CDD:280848	41/140 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464053
Domainoid	1	1.000	94	1.000	Domainoid score	I7396
eggNOG	1	0.900	-	-		E1_KOG3780
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	43	1.000	Inparanoid score	I2088
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110793at6960
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	1	1.000	-	-		otm24709
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11188
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X122
	10	9.900