DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14696 and txnipa

DIOPT Version :9

Sequence 1:	NP_650035.1	Gene:	CG14696 / 41317	FlyBaseID:	FBgn0037853	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_956381.1	Gene:	txnipa / 368359	ZFINID:	ZDB-GENE-030804-10	Length:	400	Species:	Danio rerio

Alignment Length:	446	Identity:	90/446 - (20%)
Similarity:	156/446 - (34%)	Gaps:	117/446 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSSKV---NFVFDSNPLGLYQAGQLISGTAELITERPKTIRSIFITINGYG--ETRWQESEERVG 60
            |:.:|   ...|:......|.:|..::|  :::.|..:..|.:.:.:.|.|  :..:.:.::|..
Zfish     4 MTKRVKVFEIAFNDPSKTFYCSGDKVAG--KVLVEVSEVTRVMAMKVLGVGCAKVEYAKGKQRCR 66

  Fly    61 EDGKTTK-----SLVTHTTTEVYYSTDQPVYGQAGGSQLELPTGKYVFPFRATIPPNAP--TSFN 118
            |:....|     .|..|.|..             .||.:..|..||.:.|...:|....  :|:.
Zfish    67 EEVDYLKYEDVVQLDEHPTDN-------------DGSVILRPGNKYEYSFGFELPAQGQLVSSYK 118

  Fly   119 GAHGQIKHEVTLTIDRAVRYNNTFKQCFTVILPHDLNRRLEYKEPLQRLESKSFWWGSIFGAHKP 183
            |..|.:::.|...::|..:.....|:.|.|..|.|:|.. :...|...::.|           |.
Zfish   119 GKFGFVQYYVKALMERPCQPALECKKHFEVEEPLDVNTP-DLLSPTGGMKEK-----------KV 171

  Fly   184 MIMDVSTSYSAYVPGQKIHFHLVLDN----QSDVQCMDV------------KVRLIKNVSYRANS 232
            ..|        ::|..::..:..:|.    :.:..|:|.            |..::...:|:||.
Zfish   172 TCM--------FIPDGQVSLNAKIDRRGFCEGEEICIDAKFENTCSRIVVPKAAIVAKQTYQANG 228

  Fly   233 SGAKEQLKVTESR-------VADKHCGEVLKHNKAKFDEFLTVPPTTPSTQSEKDPIRVSYTLRF 290
            .....:.|::..|       :.|...|:.::           ||...||... .:.|||.|.|..
Zfish   229 RTKVFRQKLSSVRGNHIISGMCDAWQGKSIR-----------VPKIKPSILG-CNIIRVEYALMI 281

  Fly   291 IAKTFKLHGGGDLVMDFPITIGTVPLLG---------SADDKGPGAEKS-----QPSGASHPGSP 341
            .   ..:.|...|:::.|:.|||||..|         |.|.....|..|     .||.|. |...
Zfish   282 Y---MHIPGSEKLILELPLVIGTVPYNGFGSRTNSMSSQDGSISNASNSWVSLRMPSSAP-PSYC 342

  Fly   342 NFQEDVSDEQFESNTFKPRYPVYP----FDGKPGTNGSNGAA-NFPSL--YPKAEE 390
            :...|...:|          |:.|    :||.......|.|. .||.|  |.:.||
Zfish   343 DITRDCCIDQ----------PLTPLLDDYDGGDSPIFMNAAQFQFPPLPAYSEVEE 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14696	NP_650035.1	Arrestin_N	5..155	CDD:278754	32/161 (20%)
CG14696	NP_650035.1	Arrestin_C	182..313	CDD:280848	27/153 (18%)
txnipa	NP_956381.1	Arrestin_N	11..155	CDD:304627	31/158 (20%)
txnipa	NP_956381.1	Arrestin_C	178..304	CDD:214976	27/140 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311636at33208
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	1	1.000	-	-		otm24709
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X122
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.820