DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14696 and Arrdc1

DIOPT Version :9

Sequence 1:	NP_650035.1	Gene:	CG14696 / 41317	FlyBaseID:	FBgn0037853	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	XP_038961502.1	Gene:	Arrdc1 / 366001	RGDID:	1309961	Length:	466	Species:	Rattus norvegicus

Alignment Length:	510	Identity:	112/510 - (21%)
Similarity:	180/510 - (35%)	Gaps:	140/510 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LYQAGQLISGTAELITERPKTIRSIFITINGYGETRWQESEERVGEDGKTTKSLVTHTTTEVYYS 80
            :|..|:.::|...|....|...|:|.:|..|           ..|...|....  .....|.|::
  Rat    17 VYSPGEPLAGAVHLRLGAPLPFRAIRVTCMG-----------SCGVSNKANDG--AWVVEESYFN 68

  Fly    81 TDQPVYGQAGGSQLELPTGKYVFPFRATIPPNAPTSFNGAHGQIKHEVTLTIDRAVRYNNTFKQC 145
            :...:..:  ||   ||.|::.|||:..:|..|||||.|..|:|.|:|..:|| ..|::...| |
  Rat    69 SSLSLADK--GS---LPPGEHNFPFQFLLPATAPTSFEGPFGKIVHQVRASID-TPRFSKDHK-C 126

  Fly   146 ---FTVILPHDLNRRLEYKEPLQRLESKSFWW-----GSIFGAHKPMIMDVSTSYSAYVPGQKIH 202
               |.::.|.:||...:.::|.....:|.|.:     ||:       ::..||....||.||.:.
  Rat   127 SLVFYILSPLNLNSIPDIEQPNVASTTKKFSYKLVKTGSV-------VLTASTDLRGYVVGQVLR 184

  Fly   203 FHLVLDNQSDVQCMDV-----KVRLI---------------------------KNVSYRA----- 230
            ....::|||......|     :||.|                           :.|||:|
  Rat   185 LQADIENQSGKDTSPVVASLLQVRAIWFPEPVPFPWDRRGGCQPAQTHSPVFPQKVSYKAKRWIY 249

  Fly   231 --------NSSGAKEQLKVTESRVADKHCGEVLKHNKAKFDEFLTVPPTTPSTQSEKDPIRVSYT 287
                    ..:|.|          |.:|         |::.|.:.||....|.......|.:.|.
  Rat   250 DVRTIAEVEGTGVK----------AWRH---------AQWQEQILVPALPQSALPGCSLIHIDYY 295

  Fly   288 LRFIAK------TFKLHGGGDLVMDFPITIGTVPLLGSADDKG------PGAEKSQPSGASHPGS 340
            |:...|      |..|..|...|...|::    |..|.....|      |.|...:.:.|...|
  Rat   296 LQVSMKAPEATVTLPLFVGNIAVNQTPLS----PCPGPGSSPGLLSPVVPSAPPQEEAEAVASG- 355

  Fly   341 PNFQEDVSDEQFESNTFKPRYPVYPFDGKPGTNGSNGAANFPSLYPKAEEAHPATPVKFTPNPVS 405
            |:|.:.||   ..:.:...:.|:         :.:.|:.:..::.|..:...||......|..:|
  Rat   356 PHFSDPVS---LSTKSHSQQQPL---------STTLGSVSVTTIEPCVQVGSPARHSLHPPLCIS 408

  Fly   406 PAAQKSPPYTTNTPVASPPGGNFEVL-GFSIPPDYK----PTPSAPAASSTGGIG 455
            ..|  :.||     .|...||..... ...:||:|.    |..:.|:...:.|.|
  Rat   409 IGA--TVPY-----FAEGSGGPVPTTSALILPPEYSSWGYPYEAPPSYEQSCGAG 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14696	NP_650035.1	Arrestin_N	5..155	CDD:278754	39/141 (28%)
CG14696	NP_650035.1	Arrestin_C	182..313	CDD:280848	35/181 (19%)
Arrdc1	XP_038961502.1	Arrestin_N	7..139	CDD:419887	39/141 (28%)
Arrdc1	XP_038961502.1	Arrestin_C	162..316	CDD:214976	35/179 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311636at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11188
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X122
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920