DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14696 and SPCC584.15c

DIOPT Version :9

Sequence 1:	NP_650035.1	Gene:	CG14696 / 41317	FlyBaseID:	FBgn0037853	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_588220.1	Gene:	SPCC584.15c / 2539284	PomBaseID:	SPCC584.15c	Length:	594	Species:	Schizosaccharomyces pombe

Alignment Length:	476	Identity:	90/476 - (18%)
Similarity:	167/476 - (35%)	Gaps:	119/476 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 DSNPLGLY----QAGQLISGTAELITERPKTIRSIFITINGYGETRWQESEERVGEDGKTTKSLV 70
            ::|.:.||    .....:||...|....|..:::|.:.::|.....|.: |.|....|...:..|
pombe    24 EANVIVLYGNSMDTSARLSGIVVLSVSSPIRVKNIKLRLSGRSFVCWAD-ESRHASPGNRIRRQV 87

  Fly    71 THTTTEVYYSTDQPVYGQAGGSQLELPTGKYVFPFRATIPPNAPTSFNGAHG-QIKHEVTLTIDR 134
            .....:.:      .:.....|...:..|.|.:||...:||:.|.|..|..| .|.:.:|.:::|
pombe    88 VQILDKSW------SFLAPNESAKVIDQGNYEYPFYYELPPDIPDSIEGIPGCHIIYTLTASLER 146

  Fly   135 AVRYNNTFKQCFTVILPHDLNRRLEYK-------EPLQRLESKS---FWWGSIFGAHKPMIMDVS 189
            |.:            .|.:|...|:::       ..|..:.|.|   .|         |:.::..
pombe   147 ATQ------------PPTNLETALQFRVIRTIPPNSLDLMHSVSVSDIW---------PLKVNYE 190

  Fly   190 TSY--SAYVPGQKIHFHLVLDNQSDVQCMDV-KVRLIKN------VSYRANSSGAKEQLK----- 240
            ||.  ..|..|.:|..::.|  ...::.:|| ||.|:..      ::.:|.||..:::.|
pombe   191 TSIPSKVYAIGSEIPVNITL--YPLLKGLDVGKVTLVLKEYCTLFITSKAYSSTCRKEFKRALVK 253

  Fly   241 --VTESRVADKHCGEVLKHNKAKFDEFLTVPPTTPSTQSEKD--PIRVSYTLRFIAKTFKLHGG- 300
              :....:.|.:..:.:         .:.:|.:......:.|  .|||.:.||.........|.
pombe   254 KTIPGLPMVDDYWQDQI---------MVKIPDSLGECTQDCDLNCIRVHHKLRLSISLLNPDGHV 309

  Fly   301 GDLVMDFPITIGTVPLLGSADDKGPGAEKSQPSGASHPGSPNFQEDVSDEQFESNTFKPRYPVYP 365
            .:|....|:::...|::..|          :|:.....|..|        .:.:....|.|..:.
pombe   310 SELRNSLPLSLVISPVMFGA----------RPTEGVFTGDHN--------SYVNENILPSYDKHV 356

  Fly   366 F----DGKPGTNGS-NGAANFPSLYPK-AEEAHPATPVKFTPNPVSPAAQK--SPPYTTN----- 417
            |    ||.|..|.. ......|:|..: :.:..|.:||....|||..:.|:  ||...:|
pombe   357 FDVLWDGIPSENPQLQSGFTTPNLSRRNSSDFGPNSPVNIHSNPVPISGQQPSSPASNSNANFFF 421

  Fly   418 ---------------TPVASP 423
                           :|:.||
pombe   422 GSSPQSMSSEQTDMMSPITSP 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14696	NP_650035.1	Arrestin_N	5..155	CDD:278754	30/149 (20%)
CG14696	NP_650035.1	Arrestin_C	182..313	CDD:280848	27/149 (18%)
SPCC584.15c	NP_588220.1	Arrestin_N	41..166	CDD:304627	29/143 (20%)
SPCC584.15c	NP_588220.1	Arrestin_C	183..324	CDD:214976	28/160 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	52	1.000	Domainoid score	I3293
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11188
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910