Protein Alignment CG14696 and arrd-22

DIOPT Version :10

• Sequence 1: NP_650035.1
• Gene: CG14696 / 41317
• FlyBaseID: FBgn0037853
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_503955.1
• Gene: arrd-22 / 188642
• WormBaseID: WBGene00020612
• Length: 456
• Species: Caenorhabditis elegans
• Alignment Length: 488
• Identity: 115/488 - (23%)
• Similarity: 189/488 - (38%)
• Gaps: 91/488 - (18%)

  Fly     8 VFDSNPLGLYQAGQLISGTAELITERPKTIRSIFITINGYGETRWQESEERVGEDGKTTKSLVTH 72
            :|| .|..::..||.|||...|.|::..:.|::.|.|.|...|.|:..|...   ..:...:|::
 Worm    10 IFD-QPDEVFLPGQPISGRVVLTTKKKLSARAVNIKIVGLAHTSWKNYENSC---KLSFHRIVSY 70

  Fly    73 TTTEVYYSTDQPV--YGQ----AGGSQLELPTGKYVFPFRATIPPNAPTSFNGAHGQIKHEVTLT 131
            ....||||.:...  |.|    .|....||..|:|.:||..|:|.|.|.||.|.:|.:::.|.:.
 Worm    71 RPHGVYYSANVKYLDYTQLLWTCGEGPKELNAGEYAWPFSYTLPLNIPPSFEGKYGYLRYTVKVE 135

  Fly   132 IDRAVRYNNTFKQCFTV-------ILPHDLNRRLEYKEPLQRLESKSFWWGSIFGAHKPMIMDVS 189
            :||..|.:...|.|.||       ::||.|.       |:....|::.  |.....:..:.|:|:
 Worm   136 VDRPWRVDKAKKMCITVSPLLDLNVIPHSLT-------PINTQASENL--GCCCFKNGFLEMNVN 191

  Fly   190 TSYSAYVPGQKIHFHLVLDNQSDVQCMDVKVRLIKNVSYRANSSGA------------KEQ--LK 240
            ...:.:|||:.:..::.|.|.|......::.::::...:.....||            |.|  :.
 Worm   192 IPKTGFVPGETVPLNIHLINHSSSTAKKIEAKILQQCKFTGYKDGATYNYGGDENMSEKAQRIMF 256

  Fly   241 VTESRVADKHCGEVLKHNKAKFDEFLTVPPTTPSTQSEKDPIRVSYTLRFIAKTFKLHGGGDLVM 305
            .|::.|.:.....|...|:.||...|.:|..||:.......:.|.|.::....|..: ...::..
 Worm   257 DTKTVVRESQKLVVAAKNEHKFVLELRIPSVTPTINQFSPVVTVEYLIQLKVDTSAM-SHSEVRC 320

  Fly   306 DFPITIGTVP----LLGSADDKGPGAEKSQPS----GASHPGSPNFQEDVSDEQFESNTFKPRYP 362
            :..|.:|:||    |..|...:.|....|:|:    |.:.|  |.:......:..|..|..|
 Worm   321 ETSILLGSVPIRQCLPPSYYQQDPSVLPSKPTPIGEGVAPP--PGYGSLPMTDDSEKGTDAP--- 380

  Fly   363 VYPFDGKPGTNGSNGAANFPSLYPKAEEAHPATPVKFTPNPVSPAAQKS--------------PP 413
             ||....|..|..|  ..:||:........|:.|        .|:.|:|              .|
 Worm   381 -YPLGLYPNVNDVN--LPYPSVVQDGNAVIPSAP--------PPSYQESMYGKGGTVLDAKENEP 434

  Fly   414 YTTNTPVASPPGGNFEVLGFSIPPDYKPTPSAP 446
            |....||            |:..|.|.||...|
 Worm   435 YVPKYPV------------FNNLPVYNPTAPPP 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14696	NP_650035.1	Arrestin_N	5..155	CDD:425619	49/159 (31%)
		Arrestin_C	182..316	CDD:460676	29/151 (19%)
		PHA03247	<313..450	CDD:223021	35/156 (22%)
arrd-22	NP_503955.1	Arrestin_N	7..159	CDD:425619	47/152 (31%)
		Arrestin_C	182..330	CDD:214976	27/148 (18%)