DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14696 and arrd-7

DIOPT Version :9

Sequence 1:	NP_650035.1	Gene:	CG14696 / 41317	FlyBaseID:	FBgn0037853	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_496567.2	Gene:	arrd-7 / 174847	WormBaseID:	WBGene00012464	Length:	419	Species:	Caenorhabditis elegans

Alignment Length:	472	Identity:	127/472 - (26%)
Similarity:	199/472 - (42%)	Gaps:	100/472 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 PLGLYQAGQLISGTAELITERPKTIRSIF--ITINGYGETRWQESEERV-----GEDGKTTKSLV 70
            |..:|..||.::|  ::|.:..:.|::.|  |.|:|...|.|.||....     ||..:.|:::.
Worm    11 PNDVYFPGQAVTG--KVIIQNREWIKARFLKICIHGGAHTHWSESRSTYRTNTRGERERFTENVN 73

  Fly    71 THTTTEVYYSTDQPVYGQAGGSQLELPTGKYVFPFRATIPPNAPTSFNGAHGQIKHEVTLTIDRA 135
            .:.|  :.|.|.:.:..|:......||.|..||||...:|.|...||.|.||.|:::|.:.:||.
Worm    74 YNAT--INYLTGESIAWQSRDGTDRLPAGTNVFPFAFNLPINCAPSFEGCHGHIRYDVHVELDRP 136

  Fly   136 VRYNNTFKQCFTVILPHDLNRRLEYKEPLQRLESKSFWWGSIFGAHKPMI-MDVSTSYSAYVPGQ 199
            .::|...::||:||...|||.......|:....||:  .|.|.  .|.:: :.|:.....||.|:
Worm   137 WKFNKKSRKCFSVIPVFDLNITPTAINPMVNTASKN--TGLIL--KKGLVTITVNLPKRGYVAGE 197

  Fly   200 KIHFHLVLDNQSDVQCMDVKVRLIK----------NVSYRANSSGAKEQLKVTES-RVAD---KH 250
            .:...:.:||.|.|...:|..::.:          .:...|::....::..|.|| ||||   |.
Worm   198 IMPITVNIDNGSKVAVSEVSAKMTQLSHFHASHGNMIGVTAHTHNRNDEKLVAESRRVADVPAKS 262

  Fly   251 CGEVLKHNKAKFDEFLTVPPTTPSTQSEKDP-IRVSYTLRFIAKTFKLHGGGDLVMDFPITIGTV 314
            .|:::...|        :|...||...   | |.|.|.|.....|.::.||| |..:||:.|||:
Worm   263 RGQMVLSMK--------IPAIVPSFNC---PIIAVDYCLTVKVSTQQIFGGG-LKCEFPLIIGTI 315

  Fly   315 PLLGSADDKGPGAEKSQPSGASHPGSPNFQEDVSDEQFESNTFKPRYPVYPFDGKPGTNGSNGAA 379
            | :...:...|||..:.||.::                      |.|||..           ||:
Worm   316 P-IRQMNQAAPGAMPTMPSVSA----------------------PPYPVVA-----------GAS 346

  Fly   380 NFPSLYPKAEEAHPATPVKFTP----------NPVSPAAQKSPPYTTNTPVAS--PPGGNFEVLG 432
            ...::||.|..|.||:|....|          ..|..|...:|.|    ||.:  |...|.:
Worm   347 ASQAVYPTAPSAPPASPGGEAPPSYEESVHGAGKVEDAEAFAPRY----PVYNNLPQQQNSQ--- 404

  Fly   433 FSIPPDYKPTPSAPAAS 449
              :||:|  .|..||.|
Worm   405 --LPPEY--APPLPAKS 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14696	NP_650035.1	Arrestin_N	5..155	CDD:278754	46/148 (31%)
CG14696	NP_650035.1	Arrestin_C	182..313	CDD:280848	37/146 (25%)
arrd-7	NP_496567.2	Arrestin_N	4..156	CDD:334019	46/148 (31%)
		Arrestin_C	178..316	CDD:214976	39/149 (26%)
		PRK14951	<316..>415	CDD:237865	32/143 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46400
OrthoDB	1	1.010	-	-		D311636at33208
OrthoFinder	1	1.000	-	-		FOG0000089
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11188
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X122
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.930