DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14696 and arrdc1a

DIOPT Version :9

Sequence 1:	NP_650035.1	Gene:	CG14696 / 41317	FlyBaseID:	FBgn0037853	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	XP_005171840.1	Gene:	arrdc1a / 100006005	ZFINID:	ZDB-GENE-030925-15	Length:	447	Species:	Danio rerio

Alignment Length:	487	Identity:	113/487 - (23%)
Similarity:	194/487 - (39%)	Gaps:	105/487 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 FDSNPLGLYQAGQLISGTAELITERPKTIRSIFITINGYGETRWQESEERVGEDGKTTKSLVTHT 73
            ||:|.. :|..|:.::||.::...:....::|.:...|:              .|.|:||..|..
Zfish    11 FDNNKT-VYSPGESLTGTLKISIAQSIQCKAIKVNCQGF--------------CGVTSKSNDTDW 60

  Fly    74 TTEVYYSTDQPVYGQAGGSQLELPTGKYVFPFRATIPPNAPTSFNGAHGQIKHEVTLTIDRAVRY 138
            |.|..|.:........|    .|..|::.|||:..:|..|||||.|.:|||.:.|...|| ..|:
Zfish    61 TDEEQYFSSSVSIADKG----TLKEGEHSFPFKFLLPAAAPTSFVGPYGQIMYRVRAFID-TPRF 120

  Fly   139 NNTFK--QCFTVILPHDLNRRLEYKEPLQRLESKSFWWGSIFGAHKPMIMDVSTSYSAYVPGQKI 201
            ...:|  :.|::....:||.....:||.....:|:|.:  :...:..::::..|....|:.||.|
Zfish   121 AKDYKIEKPFSMTNTLNLNEVPGIREPSSSSVTKNFSY--MLVKNGTVVLNAKTDMRGYIAGQII 183

  Fly   202 HFHLVLDNQSDVQCMDVKVRLIKNVSYRANSSGAKEQLKVTESRVADKHCGEVLKHNKAKFDEFL 266
            .....::|:||.....|...|::.|:|  |:......|:    .||:.....|...||:::::.:
Zfish   184 KVSAGIENKSDKTTGHVVASLMQKVTY--NTKKPTYDLR----SVAEVEGPGVKGGNKSEWNQQI 242

  Fly   267 TVPPTTPSTQSEKDPIRVSYTLRFIAKTFKLHGGGDLVMDFPITIGTVPLLGSADDKGPGAEKSQ 331
            .||....|:.|:.:.|::.|.::...|.      .::.:..||.||:|.|           :.||
Zfish   243 IVPALPHSSLSDGNLIQICYYIQVYLKY------PEVALTLPICIGSVAL-----------DPSQ 290

  Fly   332 PS--------------GASHPGSPNFQEDVSDEQFESNTFKPRYPVYPFDGKPGTNGSNGAANFP 382
            ||              .|..|.:|         :.|::...||....|.. ||....::.:.:.|
Zfish   291 PSHSQTVAPMPAPRITPAPSPSAP---------ESEASNLPPRPAPKPAP-KPRPRSTHASPSAP 345

  Fly   383 --SLYP-------------KAEEAHPATPVKFTPNPVSPAAQKSPP-------YTTNTPVASPPG 425
              .|||             |:....|.     :..||||.|....|       .:::.|.|.||.
Zfish   346 PVDLYPQLPSVSNYNGEMLKSPHQEPG-----SQGPVSPNAFSYAPGLSFRQRQSSSGPSAPPPS 405

  Fly   426 -------GNFEVLGFSIPPDYKPTPSAPAASS 450
                   .|......|:||.|:.:....|.:|
Zfish   406 LSSSSQDRNQMPSSASVPPSYRSSAYPQATNS 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14696	NP_650035.1	Arrestin_N	5..155	CDD:278754	39/147 (27%)
CG14696	NP_650035.1	Arrestin_C	182..313	CDD:280848	29/130 (22%)
arrdc1a	XP_005171840.1	Arrestin_N	7..139	CDD:304627	39/147 (27%)
arrdc1a	XP_005171840.1	Arrestin_C	162..283	CDD:280848	29/132 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579462
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3780
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D311636at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11188
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.850