Protein Alignment Tpc1 and LEU5

DIOPT Version :10

• Sequence 1: NP_650034.1
• Gene: Tpc1 / 41316
• FlyBaseID: FBgn0037852
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_011865.1
• Gene: LEU5 / 856391
• SGDID: S000001044
• Length: 357
• Species: Saccharomyces cerevisiae
• Alignment Length: 345
• Identity: 90/345 - (26%)
• Similarity: 148/345 - (42%)
• Gaps: 79/345 - (22%)

  Fly    33 LAGGLSAAITRSTCQPLDVLKIRFQLQVEPLGKNAAKEGPGALTS-----KYTS--IG--QAVKT 88
            ||||:|.:..::...|||.:||.||                  ||     |||.  ||  :|.|.
Yeast    38 LAGGISGSCAKTLIAPLDRIKILFQ------------------TSNPHYTKYTGSLIGLVEAAKH 84

  Fly    89 IYREEGMLAFWKGHNPAQVLSIMYGICQFWTYEQLS---LMAKQTSYLADHQHLSNFLCGAAAGG 150
            |:..:|:..|::||:...:....|...:|..|||:.   :.:|:.     ..|....:.|:.||.
Yeast    85 IWINDGVRGFFQGHSATLLRIFPYAAVKFVAYEQIRNTLIPSKEF-----ESHWRRLVSGSLAGL 144

  Fly   151 AAVIISTPLDVIRTRLIAQDTSKGYRNATRAVSAIVRQEGPR----------------GMYRGLS 199
            .:|.|:.|||::|.|| |.:|........|.:..|.::....                ..|||..
Yeast   145 CSVFITYPLDLVRVRL-AYETEHKRVKLGRIIKKIYKEPASATLIKNDYIPNWFCHWCNFYRGYV 208

  Fly   200 SALLQITPLMGTNFMAYRLFSD-------WACAFLEVSD-----------RSQLPTWTLLGLGAS 246
            ..:|.:.|..|.:|.|:.|..|       ...:.||:|:           |..|.||..|..|..
Yeast   209 PTVLGMIPYAGVSFFAHDLLHDVLKSPFFAPYSVLELSEDDELERVQKKQRRPLRTWAELISGGL 273

  Fly   247 SGMLSKTIVYPFDLIKKRLQIQGFESNRQTFGQTLQCH---GVWDCLRLTVRQEGVRGLYKGVAP 308
            :||.|:|..|||::|::|||:.....      :|:..|   .:.:...:..::.||||.:.|::.
Yeast   274 AGMASQTAAYPFEIIRRRLQVSALSP------KTMYDHKFQSISEIAHIIFKERGVRGFFVGLSI 332

  Fly   309 TLLKSSMTTALYFSIYDKLK 328
            ..:|.:...|..|.:|:::|
Yeast   333 GYIKVTPMVACSFFVYERMK 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpc1	NP_650034.1	Mito_carr	29..123	CDD:395101	30/98 (31%)
		Mito_carr	153..222	CDD:395101	22/91 (24%)
		Mito_carr	233..328	CDD:395101	27/97 (28%)
LEU5	NP_011865.1	Mito_carr	32..127	CDD:395101	31/106 (29%)
		PTZ00169	38..329	CDD:240302	84/320 (26%)