DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tpc1 and AT3G21390

DIOPT Version :9

Sequence 1:	NP_650034.1	Gene:	Tpc1 / 41316	FlyBaseID:	FBgn0037852	Length:	332	Species:	Drosophila melanogaster
Sequence 2:	NP_001327267.1	Gene:	AT3G21390 / 821693	AraportID:	AT3G21390	Length:	357	Species:	Arabidopsis thaliana

Alignment Length:	307	Identity:	105/307 - (34%)
Similarity:	168/307 - (54%)	Gaps:	18/307 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 AGGLSAAITRSTCQPLDVLKIRFQLQVEPLGKNAAKEGPGALTSKYTSIGQAVKTIYREEGMLAF 98
            |||::.||:|....||||:|||||:|:||....|.|:  ..|..||..:.:..|.|:||||:..|
plant    43 AGGVAGAISRMVTSPLDVIKIRFQVQLEPTATWALKD--SQLKPKYNGLFRTTKDIFREEGLSGF 105

  Fly    99 WKGHNPAQVLSIMYGICQFWTYEQLSLMAKQTSYLADHQHLS---NFLCGAAAGGAAVIISTPLD 160
            |:|:.||.::.:.|...||....::...|..:|...:|..||   :::.||.||.||.:.|.|.|
plant   106 WRGNVPALLMVVPYTSIQFAVLHKVKSFAAGSSKAENHAQLSPYLSYISGALAGCAATVGSYPFD 170

  Fly   161 VIRTRLIAQDTSKGYRNATRAVSAIVRQEGPRGMYRGLSSALLQITPLMGTNFMAYRLFSDWACA 225
            ::||.|.:|...|.|.|...|..:||:..|.:|:|.|||..|::|.|..|..|..|..|..|:..
plant   171 LLRTVLASQGEPKVYPNMRSAFLSIVQTRGIKGLYAGLSPTLIEIIPYAGLQFGTYDTFKRWSMV 235

  Fly   226 F---------LEVSDRSQLPTWTLLGLGASSGMLSKTIVYPFDLIKKRLQIQGFESNRQTFGQTL 281
            :         ...:....|.::.|...|.:||.:||.:.:|.|::|||.|::|.:.:.: :|..:
plant   236 YNKRYRSSSSSSTNPSDSLSSFQLFLCGLASGTVSKLVCHPLDVVKKRFQVEGLQRHPK-YGARV 299

  Fly   282 QCH---GVWDCLRLTVRQEGVRGLYKGVAPTLLKSSMTTALYFSIYD 325
            :.:   .::|.|...:|.||..|||||:.|:.:|::...|:.|..|:
plant   300 ELNAYKNMFDGLGQILRSEGWHGLYKGIVPSTIKAAPAGAVTFVAYE 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tpc1	NP_650034.1	Mito_carr	29..123	CDD:278578	37/88 (42%)
		PTZ00169	33..329	CDD:240302	105/307 (34%)
		Mito_carr	153..222	CDD:278578	26/68 (38%)
		Mito_carr	233..328	CDD:278578	30/96 (31%)
AT3G21390	NP_001327267.1	PTZ00169	33..346	CDD:240302	104/305 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	77	1.000	Domainoid score	I3085
eggNOG	1	0.900	-	-		E1_KOG0752
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5982
Inparanoid	1	1.050	181	1.000	Inparanoid score	I1450
OMA	1	1.010	-	-		QHG55227
OrthoDB	1	1.010	-	-		D1454699at2759
OrthoFinder	1	1.000	-	-		FOG0001923
OrthoInspector	1	1.000	-	-		mtm1203
orthoMCL	1	0.900	-	-		OOG6_103578
Panther	1	1.100	-	-	O	PTHR24089
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2188
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840