Protein Alignment Tpc1 and slc25a43

DIOPT Version :10

• Sequence 1: NP_650034.1
• Gene: Tpc1 / 41316
• FlyBaseID: FBgn0037852
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_001004497.2
• Gene: slc25a43 / 796731
• ZFINID: ZDB-GENE-030616-69
• Length: 345
• Species: Danio rerio
• Alignment Length: 315
• Identity: 77/315 - (24%)
• Similarity: 139/315 - (44%)
• Gaps: 32/315 - (10%)

  Fly    21 RKHSTREQLHQMLAGGLSAAITRSTCQPLDVLKIRFQLQVEPLGKNAAKEGPGALTSKYTSIGQA 85
            :|.:.......::..|.:...:::...||:|:||..|     :|....|.|          ...:
Zfish     5 KKDARLTSSQSLMCVGFAGIFSKTVTSPLEVVKILSQ-----VGTFHCKRG----------FLHS 54

  Fly    86 VKTIYREEGMLAFWKGHNPAQVLSIMYGICQFWTYEQLSLMAKQTSYLADHQHLSNFLCGAAAGG 150
            ...|.:.||:.|||||:..:.:....|......||:  :::......|.|.......:.|..||.
Zfish    55 FVLICQNEGLRAFWKGNMVSCLRLFPYSAIHLATYK--NIVNLHIDELGDISQWRAIVAGGLAGI 117

  Fly   151 AAVIISTPLDVIRTRLIAQDTSK-GYRNATRAVSAIVRQEGPRGMYRGLSSALLQITPLMGTNFM 214
            :|.:.:.||:|:.||||||:..: .||....::|.|.|.||.:.:|||.|..:|...|.....:.
Zfish   118 SAALATYPLEVVETRLIAQNCQEPTYRGLLHSLSVIYRNEGLQALYRGFSLTVLGAVPFSVGCYA 182

  Fly   215 AY----RLFSDWACAFLEVSDRSQLPTWTLLGLGASSGMLSKTIVYPFDLIKKRLQIQGFESNRQ 275
            .|    :|:.:....|..:.:...         |..:..:::|:.:||:.:||::|.|.... ..
Zfish   183 VYINLDKLWQERHVRFTSLQNFIN---------GCLAAGVAQTLSFPFETVKKKMQAQSLVL-PH 237

  Fly   276 TFGQTLQCHGVWDCLRLTVRQEGVRGLYKGVAPTLLKSSMTTALYFSIYDKLKQV 330
            ..|..:..:|:.||.|..::.:||..|:.|:...::|......|.||.::..|||
Zfish   238 CGGVDVHFNGMADCFRQVIKNKGVMALWSGLTANMVKIVPYFGLLFSCFEMCKQV 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpc1	NP_650034.1	Mito_carr	29..123	CDD:395101	21/93 (23%)
		Mito_carr	153..222	CDD:395101	24/73 (33%)
		Mito_carr	233..328	CDD:395101	21/94 (22%)
slc25a43	NP_001004497.2	Solcar 1	11..100		21/105 (20%)
		PTZ00169	20..274	CDD:240302	69/280 (25%)
		Solcar 2	104..195		28/90 (31%)
		Solcar 3	199..297		24/104 (23%)