Protein Alignment Tpc1 and slc25a42

DIOPT Version :10

• Sequence 1: NP_650034.1
• Gene: Tpc1 / 41316
• FlyBaseID: FBgn0037852
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_001038918.2
• Gene: slc25a42 / 751743
• ZFINID: ZDB-GENE-060825-313
• Length: 326
• Species: Danio rerio
• Alignment Length: 311
• Identity: 85/311 - (27%)
• Similarity: 145/311 - (46%)
• Gaps: 36/311 - (11%)

  Fly    26 REQLHQMLAGGLSAAITRSTCQPLDVLKIRFQLQVEPLGKNAAKEGPGALTSKYTSIGQAVKTIY 90
            |..|:.:::|..:.|:.::...|||..||.||                 ::|...|..:|.:.||
Zfish    38 RSVLNSLVSGAFAGAVAKTAVAPLDRTKIIFQ-----------------VSSNRFSAKEAYRLIY 85

  Fly    91 R---EEGMLAFWKGHNPAQVLSIMYGICQFWTYEQL-SLMAKQTSYLADH-QHLSNFLCGAAAGG 150
            |   ::|..:.|:|::...|..|.|...||..:||. .::.|...:.... ..:...|.|:.||.
Zfish    86 RTYLKDGFFSLWRGNSATMVRVIPYAAIQFCAHEQYKGILGKYYGFQGKALPPVPRLLAGSLAGT 150

  Fly   151 AAVIISTPLDVIRTRLIAQDTSKGYRNATRAVSAIVRQEGPRGMYRGLSSALLQITPLMGTNFMA 215
            .|.||:.|||::|.|: |....:.|.|.......|.|:||.:.:|||.:..:|.:.|..|.:|..
Zfish   151 TAAIITYPLDMVRARM-AVTPKEMYSNIMDVFVRISREEGLKTLYRGFTPTILGVVPYAGLSFFT 214

  Fly   216 YRLFSDWACAFLEVSDRSQLPTWTLLGLGASSGMLSKTIVYPFDLIKKRLQIQGFESNRQTFGQT 280
            |.....   ...|.:.|:....:..|..||.:|::.::..||.|::::|:|..|...:  |:...
Zfish   215 YETLKK---THAEKTGRAHPFPYERLVFGACAGLIGQSASYPLDVVRRRMQTAGVTGH--TYSTV 274

  Fly   281 LQCHGVWDCLRLTVRQEG-VRGLYKGVAPTLLKSSMTTALYFSIYDKLKQV 330
            |      ..:|..|.:|| |||||||::...:|..:...:.|..:| |.|:
Zfish   275 L------GTMREIVAEEGIVRGLYKGLSMNWVKGPIAVGISFMTFD-LTQI 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpc1	NP_650034.1	Mito_carr	29..123	CDD:395101	25/96 (26%)
		Mito_carr	153..222	CDD:395101	22/68 (32%)
		Mito_carr	233..328	CDD:395101	26/95 (27%)
slc25a42	NP_001038918.2	PTZ00169	35..302	CDD:240302	80/292 (27%)