Protein Alignment Tpc1 and slc25a23a

DIOPT Version :10

• Sequence 1: NP_650034.1
• Gene: Tpc1 / 41316
• FlyBaseID: FBgn0037852
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: XP_068078018.1
• Gene: slc25a23a / 561939
• ZFINID: ZDB-GENE-121214-154
• Length: 486
• Species: Danio rerio
• Alignment Length: 309
• Identity: 87/309 - (28%)
• Similarity: 145/309 - (46%)
• Gaps: 37/309 - (11%)

  Fly    31 QMLAGGLSAAITRSTCQPLDVLKIRFQLQVEPLGKNAAKEGPGALTSKYTSIGQAVKTIYREEGM 95
            |::||.::.:::|:...|||.||:..|:.    |:::.|          .::...::.:.:|.|:
Zfish   196 QLMAGAVAGSVSRTGTAPLDRLKVFLQVH----GQSSDK----------GNVWSGLRAMVKEGGL 246

  Fly    96 LAFWKGHNPAQVLSIM-YGICQFWTYEQLSLM---AKQTSYLADHQHLSNFLCGAAAGGAAVIIS 156
            .|.|:| |...||.|. ....:|..|||:..:   :.:...|..|:   .|:.|:.||..|..|.
Zfish   247 TALWRG-NGINVLKIAPETAIKFLAYEQIKRLMRGSNEGGTLKVHE---RFVAGSLAGATAQTII 307

  Fly   157 TPLDVIRTRLIAQDTSKGYRNATRAVSAIVRQEGPRGMYRGLSSALLQITPLMGTNFMAYR-LFS 220
            .|::|::|||..:.|.: |.:.......|:::||.|..|:|....:|.|.|..|.:...|. |.:
Zfish   308 YPMEVLKTRLTLRKTGQ-YSSVADCAKQILQKEGVRAFYKGYLPNMLGIIPYAGIDLAVYETLKN 371

  Fly   221 DWACAFLEVS-DRSQLPTWTLLGLGASSGMLSKTIVYPFDLIKKRLQIQ-GFESNRQTFGQTLQC 283
            .|.....|.| |...|   .|:|.|..|....:...||..||:.|:|.| ..:...|....||
Zfish   372 AWLQRHTEGSADPGVL---VLVGCGTVSSTCGQLASYPLALIRTRMQAQASIKGAPQLSMLTL-- 431

  Fly   284 HGVWDCLRLTVRQEGVRGLYKGVAPTLLKSSMTTALYFSIYDKLKQVRF 332
                  .|..|.||||.|||:|:||..||.....::.:.:|:.::.:.|
Zfish   432 ------FRSIVAQEGVVGLYRGIAPNFLKVIPAVSISYVVYEHMRALIF 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpc1	NP_650034.1	Mito_carr	29..123	CDD:395101	24/92 (26%)
		Mito_carr	153..222	CDD:395101	20/69 (29%)
		Mito_carr	233..328	CDD:395101	30/95 (32%)
slc25a23a	XP_068078018.1	FRQ1	25..150	CDD:444056
		PTZ00169	186..454	CDD:240302	83/287 (29%)