DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tpc1 and aralar1

DIOPT Version :9

Sequence 1:NP_650034.1 Gene:Tpc1 / 41316 FlyBaseID:FBgn0037852 Length:332 Species:Drosophila melanogaster
Sequence 2:NP_001247368.1 Gene:aralar1 / 43616 FlyBaseID:FBgn0028646 Length:707 Species:Drosophila melanogaster


Alignment Length:328 Identity:84/328 - (25%)
Similarity:144/328 - (43%) Gaps:28/328 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 TGSTSEATTTTTPVPRRKH-STREQLHQMLAGGLSAAITRSTCQPLDVLKIRFQLQVEPLGKNAA 68
            |...:|.....:|..|... ...|..::...|..:.|:..:...|:|::|.|.|.|         
  Fly   330 THRLAEIKAVESPADRSAFIQVLESSYRFTLGSFAGAVGATVVYPIDLVKTRMQNQ--------- 385

  Fly    69 KEGPGALTSKYTSIGQAVKTIYREEGMLAFWKGHNPAQVLSIMYGICQFWTYEQLSLMAKQTSYL 133
            :.|.......|.:.....|.:.|.||.:..::|..| |::.:........|...| :..|.|...
  Fly   386 RAGSYIGEVAYRNSWDCFKKVVRHEGFMGLYRGLLP-QLMGVAPEKAIKLTVNDL-VRDKLTDKK 448

  Fly   134 ADHQHLSNFLCGAAAGGAAVIISTPLDVIRTRL-IAQDTSKGYRNATRAVSAIVRQEGPRGMYRG 197
            .:....:..|.|..||.:.|:.:.||::::.|| :|.:.:.|  :..||.| :||:.|..|:|:|
  Fly   449 GNIPTWAEVLAGGCAGASQVVFTNPLEIVKIRLQVAGEIASG--SKIRAWS-VVRELGLFGLYKG 510

  Fly   198 LSSALLQITPLMGTNFMAYRLFSDWACAFLEVSDRSQLPTWTLLGLGASSGMLSKTIVYPFDLIK 262
            ..:.||:..|.....|..|.    ...|.:...|....|. |||..||.:|:.:.::|.|.|:||
  Fly   511 ARACLLRDVPFSAIYFPTYA----HTKAMMADKDGYNHPL-TLLAAGAIAGVPAASLVTPADVIK 570

  Fly   263 KRLQIQGFESNRQTFGQTLQCHGVWDCLRLTVRQEGVRGLYKGVAPTLLKSSMTTALYFSIYDKL 327
            .|||:.. .|.:.|:      .||||..:..:.:||.|..:||.|..:.:||....:....|:.|
  Fly   571 TRLQVVA-RSGQTTY------TGVWDATKKIMAEEGPRAFWKGTAARVFRSSPQFGVTLVTYELL 628

  Fly   328 KQV 330
            :::
  Fly   629 QRL 631

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tpc1NP_650034.1 Mito_carr 29..123 CDD:278578 18/93 (19%)
PTZ00169 33..329 CDD:240302 79/296 (27%)
Mito_carr 153..222 CDD:278578 21/69 (30%)
Mito_carr 233..328 CDD:278578 30/94 (32%)
aralar1NP_001247368.1 EF-hand_7 35..99 CDD:290234
EF-hand_8 51..99 CDD:290545
EF-hand_7 81..134 CDD:290234
EFh 84..135 CDD:298682
EF-hand_7 111..173 CDD:290234
Mito_carr 350..448 CDD:278578 22/108 (20%)
PTZ00169 358..631 CDD:240302 79/298 (27%)
Mito_carr 449..539 CDD:278578 26/96 (27%)
Mito_carr 544..633 CDD:278578 31/96 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45441588
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
21.840

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