Protein Alignment Tpc1 and CG4743

DIOPT Version :10

• Sequence 1: NP_650034.1
• Gene: Tpc1 / 41316
• FlyBaseID: FBgn0037852
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_651415.1
• Gene: CG4743 / 43101
• FlyBaseID: FBgn0039357
• Length: 297
• Species: Drosophila melanogaster
• Alignment Length: 342
• Identity: 79/342 - (23%)
• Similarity: 130/342 - (38%)
• Gaps: 75/342 - (21%)

  Fly     1 MAVTTGSTSEATTTT----TPVPRRKHSTREQLHQMLAGGLSAAITRSTCQPLDVLKIRFQLQVE 61
            ||...|..|.|.:..    .||.:.|.     .|.::|||::..:......|:|.:|.|.|.:
  Fly     1 MAAELGLESAAGSVAIKMQEPVNKLKF-----FHALVAGGVAGMVVDIALFPIDTVKTRLQSE-- 58

  Fly    62 PLGKNAAKEGPGALTSKYTSIGQAVKTIYREEGMLAFWKGHNPAQVLSIMYGICQFWTYEQLSLM 126
             ||                        .:|..|....:||..||...|.......|.|||.....
  Fly    59 -LG------------------------FWRAGGFRGIYKGLAPAAAGSAPTAALFFCTYECGKQF 98

  Fly   127 AKQTSYLADHQHLSNFLCGAAAGGAAVIISTPLDVIRTRLIAQDTSKGYRNATRAVSAIVRQEG- 190
            ....:...|..:: :....:||...|.:|..|:::.:.|  :|......::..:.:....|.||
  Fly    99 LSSVTQTKDSPYV-HMAAASAAEVLACLIRVPVEIAKQR--SQTLQGNKQSGLQILLRAYRTEGL 160

  Fly   191 PRGMYRGLSSALLQITPLMGTNFMAYRLFSDWACAFLEVSDRSQLPTWT-LLGL----------G 244
            .||:|||..|.:::..|.....|..:..|.      |:         || |.|.          |
  Fly   161 KRGLYRGFGSTIMREIPFSLIQFPLWEYFK------LQ---------WTPLTGFDSTPFSVALCG 210

  Fly   245 ASSGMLSKTIVYPFDLIKKRLQIQGFES-NRQTFGQTLQCHGVWDCLRLTVRQEGVRGLYKGVAP 308
            |.:|.:|..:..|.|::|.|:.:...|| ||:...:.: .||::       .:.|..||:.|..|
  Fly   211 AVAGGISAGLTTPLDVVKTRIMLAERESLNRRRSARRI-LHGIY-------LERGFSGLFAGFVP 267

  Fly   309 TLLKSSMTTALYFSIYD 325
            .:|..::..|.:|..||
  Fly   268 RVLWITLGGAFFFGFYD 284

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpc1	NP_650034.1	Mito_carr	29..123	CDD:395101	22/93 (24%)
		Mito_carr	153..222	CDD:395101	16/69 (23%)
		Mito_carr	233..328	CDD:395101	28/105 (27%)
CG4743	NP_651415.1	PTZ00168	25..281	CDD:185494	69/313 (22%)