Protein Alignment Tpc1 and GC1

DIOPT Version :10

• Sequence 1: NP_650034.1
• Gene: Tpc1 / 41316
• FlyBaseID: FBgn0037852
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_650134.1
• Gene: GC1 / 41448
• FlyBaseID: FBgn0260743
• Length: 321
• Species: Drosophila melanogaster
• Alignment Length: 361
• Identity: 86/361 - (23%)
• Similarity: 152/361 - (42%)
• Gaps: 89/361 - (24%)

  Fly     9 SEATTTTTPVPRRKHSTREQLHQMLAGGLSAAITRSTCQPLDVLKIRFQLQVEPLGKNAAKEGPG 73
            |.:.|..||:|:.:|.....|.:::.||::..|..:...|||::|.|  ||.:.:|.|..:
  Fly     2 SSSATIATPLPQPQHQQFALLPKIINGGIAGIIGVTCVFPLDLVKTR--LQNQQIGPNGER---- 60

  Fly    74 ALTSKYTSIGQAVKTIYREEGMLAFWKGHNPAQVLSIMYGICQFWTYEQ-LSLMA------KQTS 131
                .|.|:....:..|:.||....::| :...:|.|        |.|: :.|.|      |.|:
  Fly    61 ----MYNSMFDCFRKTYKAEGYFGMYRG-SGVNILLI--------TPEKAIKLTANDYFRHKLTT 112

  Fly   132 YLADHQHLSNFLCGAAAGGAAVIISTPLDVIRTRLIAQDTSKGYR------------NATRAVSA 184
            ........|..:.|..||...:|::||:::::.::  ||..:...            :||:..|.
  Fly   113 KDGKLPLTSQMVAGGLAGAFQIIVTTPMELLKIQM--QDAGRVAAAAKLAGKTVEKVSATQLASQ 175

  Fly   185 IVRQEGPRGMYRGL-SSALLQIT------PLMGT-NFMAYR--------LFSDWACAFLEVSDRS 233
            :::.:|..|:|:|: ::.|..:|      ||..| |.:..|        :|  | |:||
  Fly   176 LIKDKGIFGLYKGIGATGLRDVTFSIIYFPLFATLNDLGPRRNDGSGEAVF--W-CSFL------ 231

  Fly   234 QLPTWTLLGLGASSGMLSKTIVYPFDLIKKRLQIQGFESNRQTFGQTLQCHGVWDCLRLTVRQEG 298
                     .|.::|..:...|.|||::|.|||........:.|      .|:.||:..|::.||
  Fly   232 ---------AGLAAGSTAALAVNPFDVVKTRLQAIKKADGEKEF------KGISDCITKTLKHEG 281

  Fly   299 VRGLYKG-------VAPTLLKSSMTTALYFSIYDKL 327
            ....:||       :||  |.....|..|..:.:.|
  Fly   282 PTAFFKGGLCRMIVIAP--LFGIAQTVYYLGVAEGL 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpc1	NP_650034.1	Mito_carr	29..123	CDD:395101	23/94 (24%)
		Mito_carr	153..222	CDD:395101	20/96 (21%)
		Mito_carr	233..328	CDD:395101	25/102 (25%)
GC1	NP_650134.1	PTZ00169	37..294	CDD:240302	70/301 (23%)