Protein Alignment Tpc1 and slc25a25a

DIOPT Version :10

• Sequence 1: NP_650034.1
• Gene: Tpc1 / 41316
• FlyBaseID: FBgn0037852
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_998422.1
• Gene: slc25a25a / 406541
• ZFINID: ZDB-GENE-040426-2396
• Length: 469
• Species: Danio rerio
• Alignment Length: 312
• Identity: 73/312 - (23%)
• Similarity: 137/312 - (43%)
• Gaps: 35/312 - (11%)

  Fly    22 KHSTREQLHQMLAGGLSAAITRSTCQPLDVLKIRFQLQVEPLGKNAAKEGPGALTSKYTSIGQAV 86
            :|.|......:::||.:.|::|:...|||.||:..|:.              ....|...:...:
Zfish   180 EHLTGMWWRHLVSGGGAGAVSRTCTAPLDRLKVLMQVH--------------GCQGKSMCLMSGL 230

  Fly    87 KTIYREEGMLAFWKGHNPAQVLSIM-YGICQFWTYEQLSLM---AKQTSYLADHQHLSNFLCGAA 147
            ..:.:|.|:.:.|:| |...|:.|. ....:|..|||:..:   :::|..:::     .|:.|:.
Zfish   231 TQMIKEGGVRSLWRG-NGINVIKIAPETALKFMAYEQIKRVMGSSQETLGISE-----RFVAGSL 289

  Fly   148 AGGAAVIISTPLDVIRTRLIAQDTSKGYRNATRAVSAIVRQEGPRGMYRGLSSALLQITPLMGTN 212
            ||..|.....|::|::|||..:.|.: |:..:.....|::.||....|:|....:|.|.|..|.:
Zfish   290 AGVIAQSTIYPMEVLKTRLALRKTGQ-YKGISDCAKHILKTEGMSAFYKGYVPNMLGIIPYAGID 353

  Fly   213 FMAYR-LFSDWACAFLEVSDRSQLPTWTLLGLGASSGMLSKTIVYPFDLIKKRLQIQGFESNRQT 276
            ...|. |.:.|...:  .::.:....:.||..|..|....:...||..||:.|:|.|........
Zfish   354 LAVYETLKNTWLQRY--GTENADPGVFVLLACGTVSSTCGQLASYPLALIRTRMQAQASVEGSSQ 416

  Fly   277 FGQTLQCHGVWDCLRLTVRQEGVRGLYKGVAPTLLKSSMTTALYFSIYDKLK 328
            ...|    |::   :..::.||..|||:|:.|..||.....::.:.:|:.:|
Zfish   417 VSMT----GLF---KQIMKTEGPTGLYRGLTPNFLKVIPAVSISYVVYEHIK 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpc1	NP_650034.1	Mito_carr	29..123	CDD:395101	21/94 (22%)
		Mito_carr	153..222	CDD:395101	18/69 (26%)
		Mito_carr	233..328	CDD:395101	23/94 (24%)
slc25a25a	NP_998422.1	FRQ1	40..141	CDD:444056
		Solcar 1	184..270		22/100 (22%)
		PTZ00169	191..445	CDD:240302	67/283 (24%)
		Solcar 2	278..363		23/90 (26%)
		Solcar 3	375..463		24/94 (26%)