Protein Alignment Tpc1 and slc25a19

DIOPT Version :9

• Sequence 1: NP_650034.1
• Gene: Tpc1 / 41316
• FlyBaseID: FBgn0037852
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_991278.1
• Gene: slc25a19 / 403024
• ZFINID: ZDB-GENE-050417-292
• Length: 313
• Species: Danio rerio
• Alignment Length: 295
• Identity: 122/295 - (41%)
• Similarity: 177/295 - (60%)
• Gaps: 15/295 - (5%)

  Fly    33 LAGGLSAAITRSTCQPLDVLKIRFQLQVEPLGKNAAKEGPGALTSKYTSIGQAVKTIYREEGMLA 97
            |||..:..:||:...||||:|||||||:|.:... :::|      ||..:.||.:.|..|||:.|
Zfish    20 LAGSAAGIVTRALISPLDVVKIRFQLQIEKVSWR-SRQG------KYWGLWQATRCILTEEGLPA 77

  Fly    98 FWKGHNPAQVLSIMYGICQFWTYEQLS-LMAKQTSYLADHQHLSNFLCGAAAGGAAVIISTPLDV 161
            |||||.|||:||:.||..||.::|.|: |:.|:|.|.:....: :|:||..|..:|.:...|||.
Zfish    78 FWKGHIPAQLLSVCYGAVQFASFEVLTELVHKKTPYNSQTAGV-HFICGGLAACSATVACQPLDT 141

  Fly   162 IRTRLIAQDTSKGYRNATRAVSAIVRQEGPRGMYRGLSSALLQITPLMGTNFMAYRLFSDWACAF 226
            :|||..||...|.|||...|:..::|..||...||||:..|:.:.|..|..|..|.:..    ..
Zfish   142 LRTRFAAQGEPKIYRNLRHAIGTMLRSGGPFTFYRGLTPTLVAVFPYAGLQFFFYNILK----KL 202

  Fly   227 LEVSD-RSQLPTWTLLGLGASSGMLSKTIVYPFDLIKKRLQIQGFESNRQTFGQTLQCHGVWDCL 290
            ||..| :|:....:|:. |:.:|::|||:.|||||||||||:.|||..|..||:....||..||:
Zfish   203 LEHQDTKSKAGLHSLIS-GSCAGVISKTLTYPFDLIKKRLQVGGFEEARLKFGEVRTYHGFVDCV 266

  Fly   291 RLTVRQEGVRGLYKGVAPTLLKSSMTTALYFSIYD 325
            ....|:||.||.:||::|:|||::::|...|..|:
Zfish   267 LRIGREEGPRGFFKGLSPSLLKAALSTGFTFFWYE 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpc1	NP_650034.1	Mito_carr	29..123	CDD:278578	42/89 (47%)
		PTZ00169	33..329	CDD:240302	122/295 (41%)
		Mito_carr	153..222	CDD:278578	25/68 (37%)
		Mito_carr	233..328	CDD:278578	42/93 (45%)
slc25a19	NP_991278.1	PTZ00169	20..290	CDD:240302	119/282 (42%)
		Mito_carr	20..110	CDD:278578	44/96 (46%)
		Mito_carr	117..203	CDD:278578	30/90 (33%)
		Mito_carr	214..303	CDD:278578	41/89 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575720
Domainoid	1	1.000	88	1.000	Domainoid score	I7919
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5982
Inparanoid	1	1.050	219	1.000	Inparanoid score	I3551
OMA	1	1.010	-	-		QHG55227
OrthoDB	1	1.010	-	-		D1454699at2759
OrthoFinder	1	1.000	-	-		FOG0001923
OrthoInspector	1	1.000	-	-		otm24543
orthoMCL	1	0.900	-	-		OOG6_103578
Panther	1	1.100	-	-	LDO	PTHR24089
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2188
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.910