DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tpc1 and CG18418

DIOPT Version :9

Sequence 1:NP_650034.1 Gene:Tpc1 / 41316 FlyBaseID:FBgn0037852 Length:332 Species:Drosophila melanogaster
Sequence 2:NP_647924.2 Gene:CG18418 / 38572 FlyBaseID:FBgn0035568 Length:311 Species:Drosophila melanogaster


Alignment Length:307 Identity:64/307 - (20%)
Similarity:125/307 - (40%) Gaps:36/307 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    31 QMLAGGLSAAITRSTCQPLDVLKIRFQLQVEPLGKNAAKEGPGAL-TSKYTSIGQAVKTIYREEG 94
            :.:.||.|..:.....||||:||.|.|:.             |.| |.:|.:..:.:..:.:.||
  Fly    17 KFVMGGTSGMLATCIVQPLDLLKTRMQIS-------------GTLGTREYKNSFEVLSKVLKNEG 68

  Fly    95 MLAFWKGHNPAQVLSIMYGICQFWTYEQLSLMAKQTSYLADHQHLSNFLCGAAAGGAAVIISTPL 159
            :|:.:.|.:...:....|...:...| |:.|...:.::......:::...|..||....:...|.
  Fly    69 ILSLYNGLSAGLLRQATYTSAKMGVY-QMELDWYRKNFGNYPSMVASMTMGIVAGAFGAMCGNPA 132

  Fly   160 DVIRTRLIAQ-----DTSKGYRNATRAVSAIVRQEGPRGMYRGLSSALLQITPLMGTNFMAYRLF 219
            :|...|:::.     :..:.|:|...|...||:.||...::||....:.:...:......:|.|.
  Fly   133 EVALIRMMSDNRLMPEDRRNYKNVGDAFVRIVKDEGVVALWRGCLPTVGRAMVVNMVQLASYSLM 197

  Fly   220 SDWACAFLEVSDRSQLPTWTLLGLGAS--SGMLSKTIVYPFDLIKKRLQIQGFESNRQTFGQTLQ 282
            .:....:|.    ..:|    |.|.|:  ||:|:.....|.|:.|.|:|.......:..:..|: 
  Fly   198 KNQLHGYLS----EGIP----LHLTAALVSGLLTSVTSMPLDMAKTRIQQMKVIDGKPEYSGTI- 253

  Fly   283 CHGVWDCLRLTVRQEGVRGLYKGVAPTLLKSSMTTALYFSIYDKLKQ 329
                 |.|:..::.||...::||..|.|::....|...|...:::.:
  Fly   254 -----DVLKKVLKNEGAFAVWKGFTPYLMRMGPHTIFSFVFLEQMNK 295

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tpc1NP_650034.1 Mito_carr 29..123 CDD:278578 21/92 (23%)
PTZ00169 33..329 CDD:240302 64/303 (21%)
Mito_carr 153..222 CDD:278578 14/73 (19%)
Mito_carr 233..328 CDD:278578 23/96 (24%)
CG18418NP_647924.2 Mito_carr 10..108 CDD:278578 23/104 (22%)
PTZ00169 18..296 CDD:240302 64/306 (21%)
Mito_carr 109..205 CDD:278578 17/95 (18%)
Mito_carr 208..300 CDD:278578 23/98 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45441595
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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