Protein Alignment Tpc1 and Tpc2

DIOPT Version :10

• Sequence 1: NP_650034.1
• Gene: Tpc1 / 41316
• FlyBaseID: FBgn0037852
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_001246511.1
• Gene: Tpc2 / 37983
• FlyBaseID: FBgn0035078
• Length: 323
• Species: Drosophila melanogaster
• Alignment Length: 311
• Identity: 132/311 - (42%)
• Similarity: 189/311 - (60%)
• Gaps: 12/311 - (3%)

  Fly    22 KHSTREQLHQMLAGGLSAAITRSTCQPLDVLKIRFQLQVEPLGKNAAKEGPGALTSKYTSIGQAV 86
            ::|...||.|.:.||::.|.||:..|||||||||||:||||:..:..        |||..:..|.
  Fly     3 ENSVVVQLMQAVGGGIAGAATRTITQPLDVLKIRFQMQVEPVTNHKG--------SKYRGVIHAF 59

  Fly    87 KTIYREEGMLAFWKGHNPAQVLSIMYGICQFWTYEQLSLMAKQTSYLADHQHLSNFLCGAAAGGA 151
            |::|.||||...::|||..|||||.|.:.|||:||||..||.|..|..:...|..|:||..||..
  Fly    60 KSVYAEEGMRGMFRGHNSGQVLSISYALVQFWSYEQLRSMAHQFDYWRERPFLMFFICGGIAGCL 124

  Fly   152 AVIISTPLDVIRTRLIAQDTS--KGYRNATRAVSAIVRQEGPRGMYRGLSSALLQITPLMGTNFM 214
            ..:.:.|.||:||:::|.|.|  :...|....:..:.:.||..|:.|||...|:|:.||:|.||:
  Fly   125 GAVAAQPFDVVRTQMVAADPSSRRSQMNTFTGLRKVYKMEGWMGLSRGLPFTLVQVFPLVGANFL 189

  Fly   215 AYRLFSDWACAFLEVSDRSQLPTWTLLGL-GASSGMLSKTIVYPFDLIKKRLQIQGFESNRQTFG 278
            .|: :.:.|....:..|:.|......|.| ||.||:|:|.||||.||:|||:|:..|:..|:|||
  Fly   190 FYK-YLNAAVLMAKPPDQRQEIHGAFLFLNGALSGVLAKMIVYPADLLKKRIQLMAFKQERKTFG 253

  Fly   279 QTLQCHGVWDCLRLTVRQEGVRGLYKGVAPTLLKSSMTTALYFSIYDKLKQ 329
            :..:|..:..|:..|.|:||:.|.|||:.|||||:.:.:|:||||||..|:
  Fly   254 RNPECPTILGCITTTFREEGIGGFYKGMLPTLLKAGLMSAVYFSIYDMFKR 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpc1	NP_650034.1	Mito_carr	29..123	CDD:395101	46/93 (49%)
		Mito_carr	153..222	CDD:395101	23/70 (33%)
		Mito_carr	233..328	CDD:395101	46/95 (48%)
Tpc2	NP_001246511.1	Mito_carr	23..99	CDD:395101	43/83 (52%)
		Mito_carr	108..194	CDD:395101	29/86 (34%)
		Mito_carr	216..307	CDD:395101	45/89 (51%)