Protein Alignment Tpc1 and Shawn

DIOPT Version :10

• Sequence 1: NP_650034.1
• Gene: Tpc1 / 41316
• FlyBaseID: FBgn0037852
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_001027071.1
• Gene: Shawn / 3772641
• FlyBaseID: FBgn0031039
• Length: 387
• Species: Drosophila melanogaster
• Alignment Length: 373
• Identity: 93/373 - (24%)
• Similarity: 147/373 - (39%)
• Gaps: 76/373 - (20%)

  Fly     1 MAVTTGSTSEATTTTTPVPRRKHSTREQLHQMLAGGLSAAITRSTCQPLDVLKIRFQLQVEPLGK 65
            ||..:.......|.|.|..|.:     .|.|:.:....|.:|.....||||:|.|.|.|.:.|..
  Fly    17 MAAASSQNPSKATMTDPRFRIR-----PLQQVASACTGAMVTACFMTPLDVIKTRLQAQQQALLS 76

  Fly    66 N------------------------AAKEGPGALTSKYTSIGQAVKTIYREEGMLAFWKGHNPAQ 106
            |                        |||..|     :::....|...|.|.||:.:.|.|.:|..
  Fly    77 NKCFLYCNGLMDHICPCGPDTPNPAAAKPAP-----RFSGTIDAFIKISRTEGIGSLWSGLSPTL 136

  Fly   107 VLSIMYGICQFWTYEQLSLMAKQTSY---------LADHQHLSNFLCGAAAGGA----AVIISTP 158
            :.::...|..|..|||.........|         ..|..|...||....||.:    ||...:|
  Fly   137 ISALPSTIIYFVAYEQFKARFTDIHYKYTRRPDTIAHDIPHPIPFLVPLLAGVSGRILAVTCVSP 201

  Fly   159 LDVIRTRLIAQDTSKGYRNATRAVSAIVRQEGPRGMYRGLSSALLQITPLMGTNFMAYRLFSDWA 223
            :::|||::.:|..:......|  :..:|:.:|..|::|||...:|:..|..|..         |.
  Fly   202 VELIRTKMQSQRMTHAEMFGT--IRQVVQSQGVLGLWRGLPPTILRDVPFSGIY---------WT 255

  Fly   224 C-AFLEVSDRSQLPTWTL-LGLGASSGMLSKTIVYPFDLIKKRLQIQG-----FESN--RQTFGQ 279
            | .:|:.|.....||::. ...||.||.::.||..|||::|...||:.     |..|  :|...:
  Fly   256 CYEYLKSSFGVVEPTFSFSFAAGAISGSVAATITTPFDVVKTHEQIEFGEKFIFSDNPPKQVATK 320

  Fly   280 TLQCHGVWDCLRLT--VRQEGVRGLYKGVAPTLLKSSMTTALYFSIYD 325
            ::       .:||.  .|..||..::.|:.|.|.|.:...|:..|.::
  Fly   321 SV-------AMRLASIYRMGGVPAIFSGLGPRLFKVAPACAIMISSFE 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpc1	NP_650034.1	Mito_carr	29..123	CDD:395101	30/117 (26%)
		Mito_carr	153..222	CDD:395101	16/68 (24%)
		Mito_carr	233..328	CDD:395101	28/103 (27%)
Shawn	NP_001027071.1	Mito_carr	39..159	CDD:395101	31/124 (25%)
		Mito_carr	178..265	CDD:395101	25/97 (26%)
		Mito_carr	268..371	CDD:395101	28/101 (28%)