DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tpc1 and slc25a16

DIOPT Version :9

Sequence 1:NP_650034.1 Gene:Tpc1 / 41316 FlyBaseID:FBgn0037852 Length:332 Species:Drosophila melanogaster
Sequence 2:NP_991112.1 Gene:slc25a16 / 324578 ZFINID:ZDB-GENE-030131-3299 Length:321 Species:Danio rerio


Alignment Length:344 Identity:92/344 - (26%)
Similarity:147/344 - (42%) Gaps:43/344 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 VTTGSTSEATTTTTPVPRRKHSTREQLHQMLAGGLSAAITRSTCQPLDVLKIRFQLQVEPLGKNA 67
            :||.:.|.......|.|.::.. ...|....|||::....:||..|||.:||..|.|        
Zfish     1 MTTEAVSSGARPQIPAPVQRDG-YYWLRSFTAGGVAGCCAKSTIAPLDRVKILLQAQ-------- 56

  Fly    68 AKEGPGALTSKYTSIGQAVKTIYREEGMLAFWKGHNPAQVLSIMYGICQFWTYEQLSLMAKQTSY 132
               .|   ..|:..:...:|.:.::||.|..:||:....:....||..||..::...........
Zfish    57 ---NP---HYKHLGVFATLKAVPKKEGFLGLYKGNGAMMIRIFPYGAIQFMAFDNYKKFLHTKVG 115

  Fly   133 LADHQHLSNFLCGAAAGGAAVIISTPLDVIRTRLIAQDTS-KGYRNATRAVSAIVRQEGP-RGMY 195
            ::.|.|  ..:.|:.||..|||.:.||||||.||..|.|. ..|.....|...|..:||. .|.|
Zfish   116 ISGHVH--RLMAGSMAGMTAVICTYPLDVIRARLAFQVTGHHRYSGIRHAFQTIYHKEGGISGFY 178

  Fly   196 RGLSSALLQITPLMGTNFMAYRLFSDWACAF---------LEVSDRSQLPTWTLLGLGASSGMLS 251
            |||...::.:.|..|.:|..:..........         |:..|...|.|...|..|..:|.::
Zfish   179 RGLIPTIIGMAPYAGFSFFTFGTLKTLGLTHFPEQLGKPSLDNPDVLVLKTQVNLLCGGVAGAIA 243

  Fly   252 KTIVYPFDLIKKRLQIQGFESNRQTFGQTL----QCHGVWDCLRLTVRQEGV-RGLYKGVAPTLL 311
            :||.||.|:.::|:|:          |.:|    :|..:...|:....|.|| :|||:|::...:
Zfish   244 QTISYPLDVARRRMQL----------GASLPDHDKCCSLTKTLKHVYSQYGVKKGLYRGLSLNYI 298

  Fly   312 KSSMTTALYFSIYDKLKQV 330
            :...:.|:.|:.|:.:|||
Zfish   299 RCVPSQAVAFTTYEFMKQV 317

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tpc1NP_650034.1 Mito_carr 29..123 CDD:278578 25/93 (27%)
PTZ00169 33..329 CDD:240302 83/311 (27%)
Mito_carr 153..222 CDD:278578 25/70 (36%)
Mito_carr 233..328 CDD:278578 26/99 (26%)
slc25a16NP_991112.1 Mito_carr 21..113 CDD:278578 25/106 (24%)
PTZ00169 25..319 CDD:240302 87/319 (27%)
Mito_carr 120..205 CDD:278578 30/86 (35%)
Mito_carr 227..319 CDD:278578 29/101 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0752
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.810

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