Protein Alignment Tpc1 and Slc25a43

DIOPT Version :10

• Sequence 1: NP_650034.1
• Gene: Tpc1 / 41316
• FlyBaseID: FBgn0037852
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_001419807.1
• Gene: Slc25a43 / 298318
• RGDID: 1559928
• Length: 329
• Species: Rattus norvegicus
• Alignment Length: 313
• Identity: 79/313 - (25%)
• Similarity: 138/313 - (44%)
• Gaps: 47/313 - (15%)

  Fly    31 QMLAGGLSAAITRSTCQPLDVLKIRFQLQVEPLGKNAAKEGPGALTSKYTSIGQAVKTIYREEGM 95
            :.|..||:.|.:.|...||::..:..|:              |.:.|....:....:.::..||.
  Rat    15 RFLCAGLAGAFSLSLTAPLELATVLAQV--------------GRVQSHSQGLWATGRRVWLSEGP 65

  Fly    96 LAFWKGHNPAQVLSIMYGICQFWTYEQLSLMAKQTSYLADHQHL---SNFLCGAAAGGAAVIIST 157
            .|.|||:..|.:......:.|...|.:..::     ::.|...:   |:.:.|:.||..:.|::.
  Rat    66 RALWKGNGVACLRLFPCSVVQLAAYRKFVVL-----FMDDLGRISQWSSIVAGSLAGMVSTIVTY 125

  Fly   158 PLDVIRTRLIAQD-TSKGYRNATRAVSAIVRQEGPRGMYRGLSSALLQITPLMGTNFMAY-RLFS 220
            |.|:|:||||.|: ....||....|:|.|.:|||...:|||.|..:|...|....:.:.| .|..
  Rat   126 PTDLIKTRLIVQNMLEPSYRGLIHALSTIYQQEGFLALYRGASLTVLGAVPFSAGSLLVYMNLEK 190

  Fly   221 DWACAFLEVSDR-SQLPTWTLLGLGASSGMLSKTIVYPFDLIKKRLQIQ-------GFESNRQTF 277
            .|.    ...|| |.|..:..:.:.|:   :|:.:.:|||.:|:::|.|       |
  Rat   191 IWT----GPRDRFSHLQNFATVCVAAA---VSQAVSFPFDTVKRKMQAQSPYLPHYG-------- 240

  Fly   278 GQTLQCHGVWDCLRLTVRQEGVRGLYKGVAPTLLKSSMTTALYFSIYDKLKQV 330
            |..:...|..||.|..|:.:||.||:.|:...|||......:.|.:::..|::
  Rat   241 GVDIHFSGAVDCFRQIVKTQGVLGLWNGLTANLLKVVPYFGVMFGMFEFCKRI 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpc1	NP_650034.1	Mito_carr	29..123	CDD:395101	19/91 (21%)
		Mito_carr	153..222	CDD:395101	25/70 (36%)
		Mito_carr	233..328	CDD:395101	26/101 (26%)
Slc25a43	NP_001419807.1	PTZ00169	16..275	CDD:240302	75/292 (26%)