Protein Alignment Tpc1 and SLC25A42

DIOPT Version :9

• Sequence 1: NP_650034.1
• Gene: Tpc1 / 41316
• FlyBaseID: FBgn0037852
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: XP_016882159.1
• Gene: SLC25A42 / 284439
• HGNCID: 28380
• Length: 382
• Species: Homo sapiens
• Alignment Length: 329
• Identity: 89/329 - (27%)
• Similarity: 150/329 - (45%)
• Gaps: 43/329 - (13%)

  Fly     9 SEATTTTTPVPRRKHSTREQLHQMLAGGLSAAITRSTCQPLDVLKIRFQLQVEPLGKNAAKEGPG 73
            :||..:::...:|.|  |:.|..:|:|.|:.|:.::...|||..||.||
Human    80 AEAVLSSSVSSKRDH--RQVLSSLLSGALAGALAKTAVAPLDRTKIIFQ---------------- 126

  Fly    74 ALTSKYTSIGQAVKTI---YREEGMLAFWKGHNPAQVLSIMYGICQFWTYEQLSLMAKQTSYLAD 135
             ::||..|..:|.:.:   |..||.|:.|:|::...|..:.|...||..:|:...:.  .||...
Human   127 -VSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRIL--GSYYGF 188

  Fly   136 HQHL----SNFLCGAAAGGAAVIISTPLDVIRTRLIAQDTSKGYRNATRAVSAIVRQEGPRGMYR 196
            ....    .....||.||..|..::.|||::|.|: |....:.|.|.......|.|:||.:.:|.
Human   189 RGEALPPWPRLFAGALAGTTAASLTYPLDLVRARM-AVTPKEMYSNIFHVFIRISREEGLKTLYH 252

  Fly   197 GLSSALLQITPLMGTNFMAYRLFSDWACAFLEVSDRSQLPTWTLLGLGASSGMLSKTIVYPFDLI 261
            |....:|.:.|..|.:|..|.....   ...|.|.|.|...:..:..||.:|::.::..||.|::
Human   253 GFMPTVLGVIPYAGLSFFTYETLKS---LHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVV 314

  Fly   262 KKRLQIQGFES-NRQTFGQTLQCHGVWDCLRLTVRQEG-VRGLYKGVAPTLLKSSMTTALYFSIY 324
            ::|:|..|... .|.:..:|         ||..||:|| |||||||::...:|..:...:.|:.:
Human   315 RRRMQTAGVTGYPRASIART---------LRTIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTF 370

  Fly   325 DKLK 328
            |.::
Human   371 DLMQ 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpc1	NP_650034.1	Mito_carr	29..123	CDD:278578	27/96 (28%)
		PTZ00169	33..329	CDD:240302	83/305 (27%)
		Mito_carr	153..222	CDD:278578	19/68 (28%)
		Mito_carr	233..328	CDD:278578	28/96 (29%)
SLC25A42	XP_016882159.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0752
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900