Protein Alignment Tpc1 and Slc25a43

DIOPT Version :9

• Sequence 1: NP_650034.1
• Gene: Tpc1 / 41316
• FlyBaseID: FBgn0037852
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_001078966.1
• Gene: Slc25a43 / 194744
• MGIID: 2684854
• Length: 341
• Species: Mus musculus
• Alignment Length: 313
• Identity: 80/313 - (25%)
• Similarity: 141/313 - (45%)
• Gaps: 47/313 - (15%)

  Fly    31 QMLAGGLSAAITRSTCQPLDVLKIRFQLQVEPLGKNAAKEGPGALTSKYTSIGQAVKTIYREEGM 95
            ::|..||:.|.:.|...||::..:..|:              |.:.|....:....:.::..||.
Mouse    15 RLLCAGLAGAFSLSLTAPLELATVLAQV--------------GKVQSHSLGLWATGRRVWLSEGP 65

  Fly    96 LAFWKGHNPAQVLSIMYGICQFWTYEQLSLMAKQTSYLADHQHL---SNFLCGAAAGGAAVIIST 157
            .|.|||:..|.:......:.|...|.:..::     ::.|...:   |:.:.|:.||..:.|::.
Mouse    66 RALWKGNGVACLRLFPCSMVQLAAYRKFVVL-----FMDDLGRISQWSSIVTGSLAGMVSTIVTY 125

  Fly   158 PLDVIRTRLIAQDT-SKGYRNATRAVSAIVRQEGPRGMYRGLSSALLQITPLMGTNFMAY-RLFS 220
            |.|:|:|||:.|:. ...||....|.|.|.:|||...:|||:|..:|...|....:.:.| .|..
Mouse   126 PTDLIKTRLMVQNVLEPSYRGLIHAFSTIYQQEGFLALYRGVSLTVLGAVPFSAGSLLVYMNLEK 190

  Fly   221 DWACAFLEVSDR-SQLPTWTLLGLGASSGMLSKTIVYPFDLIKKRLQIQ-------GFESNRQTF 277
            .|.    ...|| |.|..:..:.:.|:   :|:|:.:|||.:|:::|.|       |
Mouse   191 VWN----GPRDRFSHLQNFANVCVAAA---VSQTLSFPFDTVKRKMQAQSPYLPHYG-------- 240

  Fly   278 GQTLQCHGVWDCLRLTVRQEGVRGLYKGVAPTLLKSSMTTALYFSIYDKLKQV 330
            |..:...|..||.|..|:.:||.||:.|:...|||......:.||:::..|::
Mouse   241 GVDVHFSGAADCFRQIVKTQGVLGLWNGLTANLLKVVPYFGVMFSMFEFCKRI 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpc1	NP_650034.1	Mito_carr	29..123	CDD:278578	19/91 (21%)
		PTZ00169	33..329	CDD:240302	79/308 (26%)
		Mito_carr	153..222	CDD:278578	24/70 (34%)
		Mito_carr	233..328	CDD:278578	28/101 (28%)
Slc25a43	NP_001078966.1	Mito_carr	8..101	CDD:278578	19/104 (18%)
		Solcar 1	11..101		19/104 (18%)
		Mito_carr	102..185	CDD:278578	26/82 (32%)
		Solcar 2	105..185		26/79 (33%)
		Mito_carr	197..295	CDD:278578	31/108 (29%)
		Solcar 3	200..298		29/105 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0752
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900