Protein Alignment Tpc1 and F55A11.4

DIOPT Version :10

• Sequence 1: NP_650034.1
• Gene: Tpc1 / 41316
• FlyBaseID: FBgn0037852
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_001256365.1
• Gene: F55A11.4 / 186276
• WormBaseID: WBGene00010077
• Length: 535
• Species: Caenorhabditis elegans
• Alignment Length: 307
• Identity: 79/307 - (25%)
• Similarity: 138/307 - (44%)
• Gaps: 41/307 - (13%)

  Fly    32 MLAGGLSAAITRSTCQPLDVLKIRFQLQVEPLGKNAAKEGPGALTSKYTSIG--QAVKTIYREEG 94
            ::|||.:.|::|:...|.|.:|:..|:.                :||...:|  ..:|.::.|.|
 Worm   252 LVAGGAAGAVSRTCTAPFDRIKVYLQVN----------------SSKTNRLGVMSCLKLLHAEGG 300

  Fly    95 MLAFWKGHNPAQVLSIM-YGICQFWTYEQLSLMAKQTSYLADHQHLSNF--LC-GAAAGGAAVII 155
            :.:||:| |...|:.|. ....:|..|:||..:.::..   .::.:|.|  || |:|||..:...
 Worm   301 IKSFWRG-NGINVIKIAPESAIKFMCYDQLKRLIQKKK---GNEEISTFERLCAGSAAGAISQST 361

  Fly   156 STPLDVIRTRLIAQDTSKGYRNATRAVSAIVRQEGPRGMYRGLSSALLQITPLMGTNFMAYRLFS 220
            ..|::|::|||..:.|.:..|........:..:||.|..|:|....|:.|.|..|.:...|....
 Worm   362 IYPMEVMKTRLALRKTGQLDRGIIHFAHKMYTKEGIRCFYKGYLPNLIGIIPYAGIDLAIYETLK 426

  Fly   221 DWACAFLEVSDRSQLPTWTLLGLGASSGMLSKTIVYPFDLIKKRLQ---IQGFESNRQT-FGQTL 281
            .....:.| ::.|:.....||..|..|....:...|||.|::.|||   |..:.....| |||
 Worm   427 RTYVRYYE-TNSSEPGVLALLACGTCSSTCGQLSSYPFALVRTRLQALSITRYSPQPDTMFGQ-- 488

  Fly   282 QCHGVWDCLRLTVRQEGVRGLYKGVAPTLLKSSMTTALYFSIYDKLK 328
                    .:..::.|||.|.|:|:.|..||.....::.:.:|:|::
 Worm   489 --------FKYILQNEGVTGFYRGITPNFLKVIPAVSISYVVYEKVR 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpc1	NP_650034.1	Mito_carr	29..123	CDD:395101	23/93 (25%)
		Mito_carr	153..222	CDD:395101	17/68 (25%)
		Mito_carr	233..328	CDD:395101	28/98 (29%)
F55A11.4	NP_001256365.1	FRQ1	72..212	CDD:444056
		PTZ00169	253..511	CDD:240302	75/288 (26%)