Protein Alignment Tpc1 and F17E5.2

DIOPT Version :10

• Sequence 1: NP_650034.1
• Gene: Tpc1 / 41316
• FlyBaseID: FBgn0037852
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_510081.3
• Gene: F17E5.2 / 181399
• WormBaseID: WBGene00008924
• Length: 531
• Species: Caenorhabditis elegans
• Alignment Length: 300
• Identity: 72/300 - (24%)
• Similarity: 136/300 - (45%)
• Gaps: 25/300 - (8%)

  Fly    32 MLAGGLSAAITRSTCQPLDVLKIRFQLQVEPLGKNAAKEGPGALTSKYTSIGQAVKTIYREEGML 96
            ::|||::.|::|:...|.|.:|:..|:       |:.|      |:| ..:...|..::.|.|:.
 Worm   248 LVAGGVAGAMSRTCTAPFDRIKVYLQV-------NSTK------TNK-LGVVSCVHLLHAEGGIK 298

  Fly    97 AFWKGHNPAQVLSIM-YGICQFWTYEQLSLMAKQTSYLADHQHLSNFLCGAAAGGAAVIISTPLD 160
            :||:| |...|:.|. ....:|..|:|:....::....|:...:...|.|::||..:.....|::
 Worm   299 SFWRG-NGINVIKIAPESAMKFMCYDQIKRWMQEYKGGAELSTIERLLAGSSAGAISQTAIYPME 362

  Fly   161 VIRTRLIAQDTSKGYRNATRAVSAIVRQEGPRGMYRGLSSALLQITPLMGTNFMAYR-LFSDWAC 224
            |::|||..:.|.:..:........:..:||.:..|:|....||.|.|..|.:...|. |.|.:..
 Worm   363 VMKTRLALRRTGQLDKGMFHFAHKMYTKEGIKCFYKGYLPNLLGIIPYAGIDLTVYESLKSMYTK 427

  Fly   225 AFLEVSDRSQLPTWTLLGLGASSGMLSKTIVYPFDLIKKRLQIQGFESNRQTFGQTLQCHGVWDC 289
            .:.|.::...|   .||..|..|....:...||..|::.|||.:.......|...|:...
 Worm   428 YYTEHTEPGVL---ALLACGTCSSTCGQLASYPLALVRTRLQARAISPKNSTQPDTMVGQ----- 484

  Fly   290 LRLTVRQEGVRGLYKGVAPTLLKSSMTTALYFSIYDKLKQ 329
            .:..::.||..|||:|:.|..:|.....::.:.:|:|:::
 Worm   485 FKHILQTEGFTGLYRGITPNFMKVIPAVSISYVVYEKVRK 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpc1	NP_650034.1	Mito_carr	29..123	CDD:395101	24/91 (26%)
		Mito_carr	153..222	CDD:395101	18/69 (26%)
		Mito_carr	233..328	CDD:395101	23/94 (24%)
F17E5.2	NP_510081.3	FRQ1	70..201	CDD:444056
		PTZ00169	249..526	CDD:240302	72/298 (24%)