Protein Alignment Tpc1 and C47E12.2

DIOPT Version :9

• Sequence 1: NP_650034.1
• Gene: Tpc1 / 41316
• FlyBaseID: FBgn0037852
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_001379107.1
• Gene: C47E12.2 / 177858
• WormBaseID: WBGene00008147
• Length: 306
• Species: Caenorhabditis elegans
• Alignment Length: 339
• Identity: 85/339 - (25%)
• Similarity: 156/339 - (46%)
• Gaps: 56/339 - (16%)

  Fly     7 STSEATTTTTPVPRRKHSTREQLH-QMLAGGLSAAITRSTCQPLDVLKIRFQLQVEPLGKNAAKE 70
            |||   .:.:|...:|.|..::.. .:|.||:||:::::...|::.:||..|:|.      :.|:
 Worm     2 STS---ASLSPAALQKRSDAQKFAIDLLIGGVSASVSKTVVAPIERVKILLQVQY------SHKD 57

  Fly    71 GPGALTSKYTSIGQAVKTIYREEGMLAFWKG-------HNPAQVLSIMYGICQFWTYEQLSL--M 126
            .|.  ..:|..|..|...:.:|:|.::||:|       :.|.|..:..:..    .|:.:.|  |
 Worm    58 IPA--DKRYNGIIDAFVRVPKEQGFVSFWRGNMTNVIRYFPTQAFNFAFND----LYKSILLKNM 116

  Fly   127 AKQTSYLADHQHLSNFLCGAAAGGAAVIISTPLDVIRTRL---IAQDTSKGYRNATRAVSAIVRQ 188
            .::.:.|:  ..:...:.|..||.:::.|..|||.|||||   |...|.:.|:.........|:.
 Worm   117 KRENNVLS--YSVRTLVSGGLAGCSSLCIVYPLDFIRTRLSADINHHTKREYKGLVDCTMKTVKN 179

  Fly   189 EGPRGMYRGLSSALLQITPLMGTNFMAYR-----LFSDWACAFLEVSDRSQLPTWTLLGLGASSG 248
            ||...:|||.:.:|        ..:..||     |:.  |......:|:.:||.:....:.....
 Worm   180 EGFSALYRGFAISL--------QTYFIYRSVYFGLYD--AIRNTINTDKKKLPFYASFAIAQGVT 234

  Fly   249 MLSKTIVYPFDLIKKRLQIQGFESNRQTFGQTLQCHGVWDCLRLTVRQEGVRGLYKGVAPTLLKS 313
            :||..:.||:|.:::|:.::|..|..:.|          ...|..|.:|||||||||....:.:|
 Worm   235 VLSSYLTYPWDTVRRRMMVKGQLSTSKAF----------SAARKIVHEEGVRGLYKGALANIFRS 289

  Fly   314 SMTTALYFSIYDKL 327
            : ..||..::|:::
 Worm   290 A-GGALVMALYEEI 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpc1	NP_650034.1	Mito_carr	29..123	CDD:278578	23/101 (23%)
		PTZ00169	33..329	CDD:240302	79/312 (25%)
		Mito_carr	153..222	CDD:278578	22/76 (29%)
		Mito_carr	233..328	CDD:278578	26/95 (27%)
C47E12.2	NP_001379107.1	PTZ00169	21..306	CDD:240302	79/317 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1857
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.950