DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tpc1 and slc-25A42

DIOPT Version :9

Sequence 1:NP_650034.1 Gene:Tpc1 / 41316 FlyBaseID:FBgn0037852 Length:332 Species:Drosophila melanogaster
Sequence 2:NP_492333.1 Gene:slc-25A42 / 172656 WormBaseID:WBGene00009666 Length:294 Species:Caenorhabditis elegans


Alignment Length:309 Identity:72/309 - (23%)
Similarity:136/309 - (44%) Gaps:52/309 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    34 AGGLSAAITRSTCQPLDVLKIRFQLQVEPLGKNAAKEGPGALTSKYTSIGQAVKTI---YREEGM 95
            ||.::.|:.::|..|||..||.||:.                :::..|...|:|.|   |||.|.
 Worm    20 AGAIAGALAKTTIAPLDRTKIYFQVS----------------STRGYSFRSAIKFIKLTYRENGF 68

  Fly    96 LAFWKGHNPAQVLSIMYGICQFWTYEQLSLMAKQTSYLADHQHLSNFLCGAAAGGAAVIISTPLD 160
            .|.::|::......:.|...||..:||...:.| .........:..::.|:.|...|.:|:.|||
 Worm    69 FALYRGNSATMARVVPYASMQFAAFEQYKKLLK-VDENGSRTPVKRYITGSLAATTATMITYPLD 132

  Fly   161 VIRTRLIAQDTSKGYRNATRAVSAIVRQEGPRGMYRGLSSALLQITPLMGTNFMAYR----LFSD 221
            ..:.|| :..:...|.:.........::.|.:.:|||:...:|.:.|..|::|..|.    ::.|
 Worm   133 TAKARL-SVSSKLQYSSLKHVFVKTYKEGGIQLLYRGIYPTILGVIPYAGSSFFTYETLKIMYRD 196

  Fly   222 WACAFLEVSDRSQLP-TWTLLGLGASSGMLSKTIVYPFDLIKKRLQIQGFESNRQTFGQTLQCHG 285
                     .|.::. ::..:..|..:|::.::..||.|::::|:|.....|.            
 Worm   197 ---------HRGEVENSYYRMLFGMLAGLIGQSSSYPLDIVRRRMQTGRIPSG------------ 240

  Fly   286 VWDCLRLTV---RQEGV-RGLYKGVAPTLLKSSMTTALYFSIYDKLKQV 330
             |..||..:   ..||: ||||||::...||..:...:.|:.|:|:.::
 Worm   241 -WSPLRALIHIYHTEGLKRGLYKGLSMNWLKGPIAVGVSFTTYEKVLEL 288

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tpc1NP_650034.1 Mito_carr 29..123 CDD:278578 25/91 (27%)
PTZ00169 33..329 CDD:240302 72/306 (24%)
Mito_carr 153..222 CDD:278578 16/72 (22%)
Mito_carr 233..328 CDD:278578 24/99 (24%)
slc-25A42NP_492333.1 PTZ00169 8..271 CDD:240302 68/290 (23%)
Mito_carr 10..100 CDD:278578 26/95 (27%)
Mito_carr 106..198 CDD:278578 20/101 (20%)
Mito_carr 203..291 CDD:278578 24/99 (24%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0752
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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