Protein Alignment Tpc1 and slc-25A42

DIOPT Version :10

• Sequence 1: NP_650034.1
• Gene: Tpc1 / 41316
• FlyBaseID: FBgn0037852
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_492333.1
• Gene: slc-25A42 / 172656
• WormBaseID: WBGene00009666
• Length: 294
• Species: Caenorhabditis elegans
• Alignment Length: 309
• Identity: 72/309 - (23%)
• Similarity: 136/309 - (44%)
• Gaps: 52/309 - (16%)

  Fly    34 AGGLSAAITRSTCQPLDVLKIRFQLQVEPLGKNAAKEGPGALTSKYTSIGQAVKTI---YREEGM 95
            ||.::.|:.::|..|||..||.||:.                :::..|...|:|.|   |||.|.
 Worm    20 AGAIAGALAKTTIAPLDRTKIYFQVS----------------STRGYSFRSAIKFIKLTYRENGF 68

  Fly    96 LAFWKGHNPAQVLSIMYGICQFWTYEQLSLMAKQTSYLADHQHLSNFLCGAAAGGAAVIISTPLD 160
            .|.::|::......:.|...||..:||...:.| .........:..::.|:.|...|.:|:.|||
 Worm    69 FALYRGNSATMARVVPYASMQFAAFEQYKKLLK-VDENGSRTPVKRYITGSLAATTATMITYPLD 132

  Fly   161 VIRTRLIAQDTSKGYRNATRAVSAIVRQEGPRGMYRGLSSALLQITPLMGTNFMAYR----LFSD 221
            ..:.|| :..:...|.:.........::.|.:.:|||:...:|.:.|..|::|..|.    ::.|
 Worm   133 TAKARL-SVSSKLQYSSLKHVFVKTYKEGGIQLLYRGIYPTILGVIPYAGSSFFTYETLKIMYRD 196

  Fly   222 WACAFLEVSDRSQLP-TWTLLGLGASSGMLSKTIVYPFDLIKKRLQIQGFESNRQTFGQTLQCHG 285
                     .|.::. ::..:..|..:|::.::..||.|::::|:|.....|.
 Worm   197 ---------HRGEVENSYYRMLFGMLAGLIGQSSSYPLDIVRRRMQTGRIPSG------------ 240

  Fly   286 VWDCLRLTV---RQEGV-RGLYKGVAPTLLKSSMTTALYFSIYDKLKQV 330
             |..||..:   ..||: ||||||::...||..:...:.|:.|:|:.::
 Worm   241 -WSPLRALIHIYHTEGLKRGLYKGLSMNWLKGPIAVGVSFTTYEKVLEL 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpc1	NP_650034.1	Mito_carr	29..123	CDD:395101	25/91 (27%)
		Mito_carr	153..222	CDD:395101	16/72 (22%)
		Mito_carr	233..328	CDD:395101	24/99 (24%)
slc-25A42	NP_492333.1	PTZ00169	8..271	CDD:240302	68/290 (23%)