DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tpc1 and PMP34

DIOPT Version :10

Sequence 1:NP_650034.1 Gene:Tpc1 / 41316 FlyBaseID:FBgn0037852 Length:332 Species:Drosophila melanogaster
Sequence 2:XP_308358.4 Gene:PMP34 / 1269711 VectorBaseID:AGAMI1_003049 Length:324 Species:Anopheles gambiae


Alignment Length:335 Identity:79/335 - (23%)
Similarity:138/335 - (41%) Gaps:80/335 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    33 LAGGLSAAITRSTCQPLDVLKIRFQLQVEPLGKNAAKEGPGALTSKYTSIGQAVKTIYREEGMLA 97
            ::|...:.|..|...|||.::.|.||: ||..:.|            .|..:.::::..|||...
Mosquito    19 VSGSAGSVIAMSAFYPLDTVRSRLQLE-EPERRKA------------LSTWRVLRSLIDEEGFET 70

  Fly    98 FWKGHNPAQVLSIMYGIC-----QFWTYEQLSLMAKQTSYLADHQHLSNFLCGAAAGGAAVIIST 157
            .::|     ::.::..:|     .|:|:..|..:.......|    |.:.|.|:.||...|:.:|
Mosquito    71 LYRG-----LVPVLESLCISNFVYFYTFHSLKALRGGGGQSA----LGDLLLGSLAGVVNVLTTT 126

  Fly   158 PLDVIRTRL----------------IAQDTSKGYRNATRAVSAIVRQEGPRGMYRG-LSSALLQI 205
            |..|:.|||                :|..:...|......:..|.|.||.||::.| :.|.:|.|
Mosquito   127 PCWVVNTRLKMKGLGQQHGKRANGPVAPGSDVQYDGLLDGLQYIARTEGVRGLWAGAVPSLMLVI 191

  Fly   206 TPLMGTNFMAYRLFSDWACAFLEVSDRSQLPTWTLLGLGASSGMLSKTIVYPFDLIKKRLQIQGF 270
            .|.:  .||.|........|  ..:.:|.....|...:||.:.|::..:.||..|::.:|:    
Mosquito   192 NPAI--QFMVYESLKRRLTA--AGNAKSSPSAITFFSIGAVAKMIATVLTYPLQLVQTKLR---- 248

  Fly   271 ESNRQTFGQTLQCHGVWD-------------CLRLTVRQEGVRGLYKGVAPTLLKSSMTTALYFS 322
                         ||..|             .|.:.::::||.||::|:...||::.:|.||.|.
Mosquito   249 -------------HGNTDRSLNLPPNVDTVQMLLIILKRQGVAGLFRGLEAKLLQTVLTAALMFM 300

  Fly   323 IYDKLKQVRF 332
            .|:|:  .||
Mosquito   301 AYEKI--ARF 308

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tpc1NP_650034.1 Mito_carr 29..123 CDD:395101 20/94 (21%)
Mito_carr 153..222 CDD:395101 23/85 (27%)
Mito_carr 233..328 CDD:395101 26/107 (24%)
PMP34XP_308358.4 Mito_carr 15..99 CDD:395101 21/97 (22%)
Mito_carr 106..208 CDD:395101 29/107 (27%)
Mito_carr 223..310 CDD:395101 26/105 (25%)

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