DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14695 and l(2)01289

DIOPT Version :9

Sequence 1:	NP_650032.1	Gene:	CG14695 / 41314	FlyBaseID:	FBgn0037850	Length:	289	Species:	Drosophila melanogaster
Sequence 2:	NP_001163065.1	Gene:	l(2)01289 / 46017	FlyBaseID:	FBgn0010482	Length:	1786	Species:	Drosophila melanogaster

Alignment Length:	263	Identity:	53/263 - (20%)
Similarity:	89/263 - (33%)	Gaps:	107/263 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 DNNSIPWILWLPPLTEVDRKSPGGRFTFDG-PKVVAFH-FVKNRH-GDTLD-----KWI------ 60
            |.:.|.::       ::|.......:..|. |.:|.|. .:.|.: ||.:|     ||:
  Fly   323 DKHGIQFV-------KIDDAKAAADYGIDSIPAIVYFEKEIPNVYDGDLMDEEQILKWLLGQLER 380

  Fly    61 --------SLLDELAQEYAGR---ILF----------GLRDISNIGE--------FNPNLNPDDF 96
                    .:||.:.:|  ||   :||          .|.::.||.:        |....||::.
  Fly   381 DEIEDVTDEMLDTMIKE--GRVIAVLFYDNNDKKSQKVLEELENIDDECDALGITFVKIDNPEEA 443

  Fly    97 GSY-----------RKGLPPRIYGKDCEGRVYDMHKLVNAKYLREFCDQLLADQLFRAVVLGATA 150
            ..|           .||: |.||    ||.:.|..||     |:...||..:||:
  Fly   444 VEYGINKVPKLIYFEKGI-PTIY----EGNLEDEEKL-----LKWLTDQTSSDQI---------- 488

  Fly   151 SLDSKPMNYFELREESSSDMLVMLYD-----PACYYWPIQKRMLRKLIRL------LASEDLPIV 204
                         |:.:.:||.::.:     ...:|...||:..:.|..|      ....|:..|
  Fly   489 -------------EDITDEMLDLIIEKMPHVAVLFYDKDQKKSQKILAELENIDDECDQNDIAFV 540

  Fly   205 IVD 207
            .:|
  Fly   541 KID 543

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14695	NP_650032.1	Thioredoxin_6	<20..134	CDD:290560	36/167 (22%)
l(2)01289	NP_001163065.1	PDI_a_family	50..145	CDD:239259
		PDI_a_family	384..479	CDD:239259	25/106 (24%)
		Thioredoxin_6	510..689	CDD:404691	8/34 (24%)
		ER_PDI_fam	700..>916	CDD:273457
		PDI_a_family	1129..1226	CDD:239259
		TRX_family	1433..>1502	CDD:239245
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0191
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900