DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14695 and pdia7

DIOPT Version :9

Sequence 1:	NP_650032.1	Gene:	CG14695 / 41314	FlyBaseID:	FBgn0037850	Length:	289	Species:	Drosophila melanogaster
Sequence 2:	NP_998070.1	Gene:	pdia7 / 405841	ZFINID:	ZDB-GENE-040426-2238	Length:	488	Species:	Danio rerio

Alignment Length:	258	Identity:	57/258 - (22%)
Similarity:	97/258 - (37%)	Gaps:	63/258 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 FVKNRHGDTLDKWISLLDELAQEYAGR-ILFGLRDISNIGEFNPNLNPDDFG--SYRKGLPPRIY 108
            :::|..|  .:.|.:.:.::|.::..| :.|.:.|..   ||...|. ::||  |...|..|.:.
Zfish   260 YLRNPKG--TNYWRNRIMKVATQFQDRGLTFAVADRQ---EFQDELE-EEFGVSSSEGGDVPLVT 318

  Fly   109 GKDCEGRVYDMHK--LVNAKYLREFCDQLLADQLFRAVVLGATASLDSKPM------NYFELREE 165
            .:...|:.|.|.:  ..:.|.|.:|.:...|.:|.|.|........:..|:      .:..:..:
Zfish   319 IRTRAGQKYSMQEEFTRDGKSLEKFLEDYFAKRLKRYVKSEPIPESNDGPVKVLVADTFDAIVND 383

  Fly   166 SSSDMLVMLYDPACYYW----PIQKRMLRKLIRLLASEDLPIVIVDK----AN----NYLGVGFT 218
            ...|:||..|.|.|.:.    |..|.:..||      ...|.:::.|    ||    ||...||
Zfish   384 PEKDVLVEFYAPWCGHCKNLEPKYKELGEKL------SGNPNIVIAKMDATANDVPPNYDVQGF- 441

  Fly   219 RWLQMVNCHGSTIF-------TSPRR--DGWDIKLSVRMESTRGYLRYIARNRQPELIDFDAD 272
                      .||:       ..|||  .|.::...:.      ||:..|.|  |.::|...|
Zfish   442 ----------PTIYFVPSGQKDQPRRYEGGREVNDFIT------YLKKEATN--PLILDDSRD 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14695	NP_650032.1	Thioredoxin_6	<20..134	CDD:290560	21/91 (23%)
pdia7	NP_998070.1	ER_PDI_fam	20..483	CDD:273457	55/253 (22%)
		Thioredoxin_like	25..124	CDD:294274
		PDI_b_ERp57	127..231	CDD:239367
		PDI_b'_ERp72_ERp57	235..348	CDD:239371	21/93 (23%)
		PDI_a_PDI_a'_C	368..471	CDD:239293	25/125 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000292
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000