Protein Alignment CG14695 and Pdia3

DIOPT Version :9

• Sequence 1: NP_650032.1
• Gene: CG14695 / 41314
• FlyBaseID: FBgn0037850
• Length: 289
• Species: Drosophila melanogaster
• Sequence 2: NP_059015.2
• Gene: Pdia3 / 29468
• RGDID: 68430
• Length: 510
• Species: Rattus norvegicus
• Alignment Length: 298
• Identity: 60/298 - (20%)
• Similarity: 110/298 - (36%)
• Gaps: 74/298 - (24%)

  Fly    21 PPLTEVDRKSPGGRFTFDGPKVVAFH---FVKNRHGDTLDKWISLLDELAQEY--AG-RILFGLR 79
            |.:||.::....|:     ..:.|::   :.||..|.  :.|.:.:..:|:.:  || ::.|.
  Rat   250 PHMTEDNKDLIQGK-----DLLTAYYDVDYEKNTKGS--NYWRNRVMMVAKTFLDAGHKLNFA-- 305

  Fly    80 DISNIGEFNPNLNPDDFG-SYRKGLPPRIYGKDCEGRVYDMHKLV--NAKYLREFCDQLLADQLF 141
             :::...|:..|:  ||| ....|..|.:..:..:|..:.|.:..  :.|.|..|..:.....|.
  Rat   306 -VASRKTFSHELS--DFGLESTTGEIPVVAIRTAKGEKFVMQEEFSRDGKALERFLQEYFDGNLK 367

  Fly   142 RAVVLGATASLDSKPM--------------NYFELREESSSDMLVMLYDPACYYW----PIQKRM 188
            |        .|.|:|:              ::.::......|:|:..|.|.|.:.    |..|.:
  Rat   368 R--------YLKSEPIPETNEGPVKVVVAESFDDIVNAEDKDVLIEFYAPWCGHCKNLEPKYKEL 424

  Fly   189 LRKLIRLLASEDLPIVIV-------DKANNYLGVGFTRWLQMVNCHGSTIFTSPRRDGWDIKLSV 246
            ..||     |:|..|||.       |..:.|...||           .||:.||.......|...
  Rat   425 GEKL-----SKDPNIVIAKMDATANDVPSPYEVKGF-----------PTIYFSPANKKLTPKKYE 473

  Fly   247 RMESTRGYLRYIARN-RQPELIDFDADGEPRALEQAVE 283
            .......::.|:.|. ..|.:|.   :.:|:..::|.|
  Rat   474 GGRELNDFISYLQREATNPPIIQ---EEKPKKKKKAQE 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14695	NP_650032.1	Thioredoxin_6	<20..134	CDD:290560	25/121 (21%)
Pdia3	NP_059015.2	ER_PDI_fam	31..492	CDD:273457	55/277 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	489..510		5/23 (22%)
		Prevents secretion from ER	507..510		1/2 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000292
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000