Protein Alignment CG14695 and P4hb

DIOPT Version :10

• Sequence 1: NP_650032.1
• Gene: CG14695 / 41314
• FlyBaseID: FBgn0037850
• Length: 289
• Species: Drosophila melanogaster
• Sequence 2: NP_037130.2
• Gene: P4hb / 25506
• RGDID: 3244
• Length: 509
• Species: Rattus norvegicus
• Alignment Length: 367
• Identity: 65/367 - (17%)
• Similarity: 124/367 - (33%)
• Gaps: 116/367 - (31%)

  Fly     5 KTYTIDNNSIPWILWL-----PPLTEVDRKSPGGRFTFDGPKVVAFHFVKNRHGDTLDKWISLLD 64
            |.||....:...:.||     |..|.:. .:.......|..:|....|.|:...|:..:::
  Rat   116 KEYTAGREADDIVNWLKKRTGPAATTLS-DTAAAESLVDSSEVTVIGFFKDAGSDSAKQFL---- 175

  Fly    65 ELAQEYAGRILFGLRDISNI---------------------GEFNPNLNPD---DFGSYRKGLP- 104
             ||.|....|.||:...|::                     ..|...:..:   ||..:.: ||
  Rat   176 -LAAEAVDDIPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNFEGEITKEKLLDFIKHNQ-LPL 238

  Fly   105 ---------PRIYGKDCEGRV----------YDMHKLVNAKYLRE-FCDQLLADQLFRAVVLGAT 149
                     |:|:|.:.:..:          || .||.|.|...| |..::|      .:.:.:.
  Rat   239 VIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYD-GKLSNFKKAAEGFKGKIL------FIFIDSD 296

  Fly   150 ASLDSKPMNYFEL-REESSSDMLVML------YDPA------------CYYW---PIQKRML--- 189
            .:.:.:.:.:|.| :||..:..|:.|      |.|.            |:::   .|:..::
  Rat   297 HTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESDELTAEKITQFCHHFLEGKIKPHLMSQE 361

  Fly   190 ------RKLIRLLASEDLPIVIVDKANNYLGVGFTRWLQMVNCHGSTIFTSPRRDGWDIKLS--- 245
                  ::.:::|..::...|..|:..|.....:..|     | |.....:|.   || ||.
  Rat   362 LPEDWDKQPVKVLVGKNFEEVAFDEKKNVFVEFYAPW-----C-GHCKQLAPI---WD-KLGETY 416

  Fly   246 --------VRMESTRGYLRYIARNRQPELIDFDADGEPRALE 279
                    .:|:||...:..:..:..|.|..|.|..:...::
  Rat   417 KDHENIVIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVID 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14695	NP_650032.1	None
P4hb	NP_037130.2	ER_PDI_fam	26..476	CDD:273457	65/367 (18%)
		Prevents secretion from ER	506..509