Protein Alignment CG14695 and P4hb

DIOPT Version :10

• Sequence 1: NP_650032.1
• Gene: CG14695 / 41314
• FlyBaseID: FBgn0037850
• Length: 289
• Species: Drosophila melanogaster
• Sequence 2: NP_035162.1
• Gene: P4hb / 18453
• MGIID: 97464
• Length: 509
• Species: Mus musculus
• Alignment Length: 368
• Identity: 67/368 - (18%)
• Similarity: 122/368 - (33%)
• Gaps: 118/368 - (32%)

  Fly     5 KTYTIDNNSIPWILWL-----PPLTEVDRKSPGGRFTFDGPKVVAFHFVKNRHGDTLDKWISLLD 64
            |.||....:...:.||     |..|.:. .:.......|..:|....|.|:...|:..:::
Mouse   116 KEYTAGREADDIVNWLKKRTGPAATTLS-DTAAAESLVDSSEVTVIGFFKDVESDSAKQFL---- 175

  Fly    65 ELAQEYAGRILFGLRDISNIGEFNP-NLNPDD---FGSYRKG---------------------LP 104
             ||.|....|.||:  .||.|.|:. .|:.|.   |..:.:|                     ||
Mouse   176 -LAAEAIDDIPFGI--TSNSGVFSKYQLDKDGVVLFKKFDEGRNNFEGEITKEKLLDFIKHNQLP 237

  Fly   105 ----------PRIYGKDCEGRV----------YDMHKLVNAKYLRE-FCDQLLADQLFRAVVLGA 148
                      |:|:|.:.:..:          || .||.:.|...| |..::|      .:.:.:
Mouse   238 LVIEFTEQTAPKIFGGEIKTHILLFLPKSVSDYD-GKLSSFKRAAEGFKGKIL------FIFIDS 295

  Fly   149 TASLDSKPMNYFEL-REESSSDMLVMLYDPACYYWP---------------------IQKRML-- 189
            ..:.:.:.:.:|.| :||..:..|:.|.:....|.|                     |:..::
Mouse   296 DHTDNQRILEFFGLKKEECPAVRLITLEEEMTKYKPESDELTAEKITEFCHRFLEGKIKPHLMSQ 360

  Fly   190 -------RKLIRLLASEDLPIVIVDKANNYLGVGFTRWLQMVNCHGSTIFTSPRRDGWDIKLS-- 245
                   ::.:::|...:...|..|:..|.....:..|     | |.....:|.   || ||.
Mouse   361 EVPEDWDKQPVKVLVGANFEEVAFDEKKNVFVEFYAPW-----C-GHCKQLAPI---WD-KLGET 415

  Fly   246 ---------VRMESTRGYLRYIARNRQPELIDFDADGEPRALE 279
                     .:|:||...:..:..:..|.|..|.|..:...::
Mouse   416 YKDHENIIIAKMDSTANEVEAVKVHSFPTLKFFPASADRTVID 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14695	NP_650032.1	None
P4hb	NP_035162.1	ER_PDI_fam	26..476	CDD:273457	67/368 (18%)
		Prevents secretion from ER	506..509