DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14695 and pdi-6

DIOPT Version :9

Sequence 1:	NP_650032.1	Gene:	CG14695 / 41314	FlyBaseID:	FBgn0037850	Length:	289	Species:	Drosophila melanogaster
Sequence 2:	NP_509190.1	Gene:	pdi-6 / 180974	WormBaseID:	WBGene00015168	Length:	440	Species:	Caenorhabditis elegans

Alignment Length:	197	Identity:	38/197 - (19%)
Similarity:	61/197 - (30%)	Gaps:	50/197 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 WISLLDELAQEYAGRILFGLRDISNIGEFNPNLNPDDFGSYR-KGLPP-RIYGKDCEGRVYDMHK 121
            |......|..||. :....|:.::.:|..:...:....|.|. :|.|. :|:|.|         |
Worm    53 WCGHCKSLVPEYK-KAASALKGVAKVGAVDMTQHQSVGGPYNVQGFPTLKIFGAD---------K 107

  Fly   122 LVNAKYLREFCDQLLADQLFRAVVLGATASLDSK-----------------------------PM 157
            .....|..:...|.:||.:........:|.|..|                             ..
Worm   108 KKPTDYNGQRTAQAIADSVLAEAKKAVSARLGGKSSGSSSSGSGSGSGKRGGGGSGNEVVELTDA 172

  Fly   158 NYFELREESSSDMLVMLYDPACYY-------WPIQKRMLRKLIRLLASEDLPIVIVDKANNYLGV 215
            |:.:|...|....||..:.|.|.:       |......|:..:||.|.:.....:|  ||.:...
Worm   173 NFEDLVLNSKDIWLVEFFAPWCGHCKSLEPQWKAAASELKGKVRLGALDATVHTVV--ANKFAIR 235

  Fly   216 GF 217
            ||
Worm   236 GF 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14695	NP_650032.1	Thioredoxin_6	<20..134	CDD:290560	15/76 (20%)
pdi-6	NP_509190.1	PDI_a_P5	25..127	CDD:239299	18/83 (22%)
		PDI_a_P5	165..269	CDD:239299	17/75 (23%)
		P5_C	278..407	CDD:239281
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0191
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900