DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14695 and Y49E10.4

DIOPT Version :9

Sequence 1:	NP_650032.1	Gene:	CG14695 / 41314	FlyBaseID:	FBgn0037850	Length:	289	Species:	Drosophila melanogaster
Sequence 2:	NP_499613.1	Gene:	Y49E10.4 / 176664	WormBaseID:	WBGene00013030	Length:	436	Species:	Caenorhabditis elegans

Alignment Length:	308	Identity:	62/308 - (20%)
Similarity:	96/308 - (31%)	Gaps:	92/308 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 NNSIPWIL-----W------LPPLTEVDRKSPGGRFTFDGPKVVAFHFVKNRHGDTLDKWISLLD 64
            |:..||::     |      |.|..:...:..|||..|                       ..||
Worm   170 NSKEPWMVEFFAPWCGHCQKLEPEWKKAAEEMGGRVKF-----------------------GALD 211

  Fly    65 ELAQEYAGRILFGLRDISNIGEFNPNLNP------------------------DDFGSYRKGLPP 105
            ..|.|...: .||:|....|..|.|..:.                        ||||:     .|
Worm   212 ATAHESIAQ-KFGIRGFPTIKFFAPGTSSASDAEDYQGGRTSTDLISYAESKYDDFGA-----AP 270

  Fly   106 RIY---GKDCEGRVYDMHKLVNAKYLREFCDQLLADQLFRAVVLGATASLDSKPMNYFELREESS 167
            .:.   ||.....|....:|....:|....|.....:..:..:|...|::..|....:...|..:
Worm   271 EVVEGTGKAVVETVCKDKQLCIFTFLPSIFDCQSKCRKQKIDMLNELATIFKKRSFGWVWMEGGA 335

  Fly   168 SDMLVMLYDPACYYWPIQKRMLRKLIRLLASEDLPIVIVDKANNYLGV---GFTRWLQMVNCHGS 229
            .:.:...::...|.:|:...|..|  :::.|..:....||....:|..   |..|.|::...|.|
Worm   336 QENVQRAFEIGDYGFPVLIAMSPK--KMMYSTQIGQFSVDGIKEFLNAVNYGKGRVLEIKPTHLS 398

  Fly   230 TIF-----TSPRRDGWDIKLSVRMESTRGYLRYIARNRQPELIDFDAD 272
            ..|     |.| .||.|.:|.| ||..             :|.|.|.|
Worm   399 NNFLKIVETQP-WDGKDKELPV-MEDI-------------DLSDVDMD 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14695	NP_650032.1	Thioredoxin_6	<20..134	CDD:290560	26/140 (19%)
Y49E10.4	NP_499613.1	PDI_a_P5	26..127	CDD:239299
		PDI_a_P5	156..259	CDD:239299	20/112 (18%)
		P5_C	269..405	CDD:239281	25/137 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0191
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900