DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14695 and M04D5.1

DIOPT Version :9

Sequence 1:	NP_650032.1	Gene:	CG14695 / 41314	FlyBaseID:	FBgn0037850	Length:	289	Species:	Drosophila melanogaster
Sequence 2:	NP_001251622.1	Gene:	M04D5.1 / 13182108	WormBaseID:	WBGene00014807	Length:	332	Species:	Caenorhabditis elegans

Alignment Length:	264	Identity:	56/264 - (21%)
Similarity:	88/264 - (33%)	Gaps:	101/264 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 DGPKVVAF-HFVKNRHGDTLDKWISLLDELAQEYAGRILFGLRDISNIGEFNPNLNPDDFGSYRK 101
            |..:||.. :|.|.      |.:::.:.||..|....|.:|:.|.|.:.   .::|.|::|..
Worm     3 DKKRVVTLAYFEKT------DFYLARIFELMYERDNDIFYGITDSSEVA---ASVNLDEYGFV-- 56

  Fly   102 GLPPRIYGKDCEGRVYDMHKLVNAKYLREFCDQLLADQLFRAVVLGATASLDSKPMNYFELREES 166
                 |..|..|||           .:|.|.:|.|| |.:.|.:..           |.|.:
Worm    57 -----IITKSKEGR-----------EMRYFSEQDLA-QDYSAFIRW-----------YHEFK--- 90

  Fly   167 SSDMLVMLYDPACYYWPIQKRMLRKLIRLLASEDLPIVIVDKANNYLGVGFTRWLQMVNC----- 226
                                              ||:||..:.|....|. ||...||:.
Worm    91 ----------------------------------LPLVITSRQNMKDAVE-TRQFNMVHVLYIKK 120

  Fly   227 ----HGSTI--FT-SPRRDGWDIKLSVRMESTRGYLRYIARNRQ----PELIDFDADGEPRALEQ 280
                :.|||  || :.||.....|:..       ::|::..:|.    |:.|.|..:..|.....
Worm   121 SDTDYNSTISKFTDTARRFHGRFKILF-------FIRHLDESRDNTYIPKRIRFLINYSPTTTPS 178

  Fly   281 AVEY 284
            :|.|
Worm   179 SVIY 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14695	NP_650032.1	Thioredoxin_6	<20..134	CDD:290560	23/96 (24%)
M04D5.1	NP_001251622.1	ER_PDI_fam	<2..329	CDD:273457	56/264 (21%)
M04D5.1	NP_001251622.1	Thioredoxin_like	229..311	CDD:294274
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000292
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000