DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sodh-2 and sord

DIOPT Version :9

Sequence 1:	NP_524311.1	Gene:	Sodh-2 / 41313	FlyBaseID:	FBgn0022359	Length:	360	Species:	Drosophila melanogaster
Sequence 2:	NP_001165890.1	Gene:	sord / 570613	ZFINID:	ZDB-GENE-040426-1231	Length:	354	Species:	Danio rerio

Alignment Length:	355	Identity:	208/355 - (58%)
Similarity:	262/355 - (73%)	Gaps:	2/355 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MATDNLTAVLHGIEDLRLEQRPIPEIADDEVLLAMDSVGICGSDVHYLAHGRIGDFVLTKPMIIG 65
            |..|||:.|||...|||||||||||...::|||.|.|||||||||||..:|||||||:.:|||:|
Zfish     1 MDKDNLSVVLHAKGDLRLEQRPIPEPGPNDVLLQMHSVGICGSDVHYWQNGRIGDFVVKQPMILG 65

  Fly    66 HEAAGVVAKLGKKVTTLKVGDRVAIEPGVPCRYCDHCKQGRYNLCADMVFCATPPYDGNLTRYYK 130
            |||:|.|.|:|..||.||.|||||:|||||....:..|.|.|||...:.||||||.||||.||||
Zfish    66 HEASGRVVKVGSAVTHLKPGDRVAVEPGVPREVDEFVKSGHYNLSPSIFFCATPPDDGNLCRYYK 130

  Fly   131 HAADFCFKLPDHVSMEEGALLEPLSVGVHACRRAGVGLGSKVLILGAGPIGLVTLLAAQAMGASE 195
            |:|.||:||||:|:.|||||:||||||:||||||||.|||.|.:.||||||||:||||:|||||:
Zfish   131 HSASFCYKLPDNVTYEEGALIEPLSVGIHACRRAGVTLGSSVFVCGAGPIGLVSLLAAKAMGASQ 195

  Fly   196 ILITDLVQQRLDVAKELGATHTLLLQRDQSAEETVKVVHQTMSEVPDKSIDCCGAESSARLAIFA 260
            ::|:||...||..|||:||...|.::::.|.::..|.|...:..:|...|:|.|.:||.:.||:|
Zfish   196 VIISDLSSDRLAKAKEIGADFLLPVKKEDSPQDLAKRVEGMLGCMPQICIECTGVQSSIQTAIYA 260

  Fly   261 TRSGGVVVVVGMGAPEVKLPLINALAREIDIRGVFRYCNDYSAALALVASGKVNVKRLVTHHYDI 325
            ||||||||.||:||....:||:||..||:||||||||||.:..|::::||.|||||.||||.:.:
Zfish   261 TRSGGVVVSVGLGAEMTTVPLLNAAVREVDIRGVFRYCNTWPVAISMLASKKVNVKPLVTHRFPL 325

  Fly   326 TETAEAFETSRRGTGGAIKVMIHVQPRDAN 355
            ....:||||:|:|.|  :|||:.....|.|
Zfish   326 EHAVQAFETTRQGLG--VKVMLKCDKNDQN 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sodh-2	NP_524311.1	PLN02702	4..346	CDD:215378	203/341 (60%)
Sodh-2	NP_524311.1	sorbitol_DH	8..349	CDD:176188	202/340 (59%)
sord	NP_001165890.1	PLN02702	4..344	CDD:215378	203/341 (60%)
sord	NP_001165890.1	sorbitol_DH	7..347	CDD:176188	202/341 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578010
Domainoid	1	1.000	153	1.000	Domainoid score	I4252
eggNOG	1	0.900	-	-		E1_COG1063
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56080
Inparanoid	1	1.050	423	1.000	Inparanoid score	I1753
OMA	1	1.010	-	-		QHG56613
OrthoDB	1	1.010	-	-		D1019156at2759
OrthoFinder	1	1.000	-	-		FOG0001480
OrthoInspector	1	1.000	-	-		otm25520
orthoMCL	1	0.900	-	-		OOG6_100349
Panther	1	1.100	-	-	LDO	PTHR43161
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X751
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.770