Protein Alignment CG4596 and Tmem169

DIOPT Version :10

• Sequence 1: NP_650031.1
• Gene: CG4596 / 41312
• FlyBaseID: FBgn0037849
• Length: 425
• Species: Drosophila melanogaster
• Sequence 2: NP_001103044.1
• Gene: Tmem169 / 690294
• RGDID: 1582820
• Length: 297
• Species: Rattus norvegicus
• Alignment Length: 272
• Identity: 93/272 - (34%)
• Similarity: 139/272 - (51%)
• Gaps: 49/272 - (18%)

  Fly   151 ESSLDAKLSKSQDCLSNRSSSKKRVNIRTSDLPGQGRNQRSSPEIANYEDLESGETSVLNNYDQS 215
            ||:|..:..:.:|      |..:.:.|..||      |:::..|                 .|:|
  Rat    34 ESTLGRRKKRRKD------SRPESIIIYRSD------NEKTDEE-----------------PDES 69

  Fly   216 LERGYQARKEGG------------------GNYLTMTGTIKRGRKKGQSVDLQINISREELEQL- 261
             |.|.:.::|.|                  ..|:|:||||.||:||||.||:.:.::.:||::|
  Rat    70 -EAGDRPKEEEGEDFLDYPGDDGMWNMPLDSRYVTLTGTITRGKKKGQMVDIHVTLTEKELQELT 133

  Fly   262 NAHAMASDTQKGGNLCCTCSCGTGLHILLISLFCLPFVTVVSAVYSFYIGTLTWYNMFNYYCEER 326
            ....::.:....|...|......|.|::|.:|.|||.|.|:|.|.|||.||:||||:|..|.|||
  Rat   134 KPQELSREAAPEGRRACQVGADQGPHVVLWTLVCLPVVFVLSFVVSFYYGTITWYNIFLVYNEER 198

  Fly   327 TYLHKILVTPLLFVIYPLAIVLCTFGLGIYSGLRQLSLQYSSWVNDITDIEKGFYGWLCGFLRMP 391
            |:.|||...|.|.:.||:.|:.....||:|:.:.|||..:::|.....|:||||.||||..|.:.
  Rat   199 TFWHKISCCPCLILFYPVLIMAMASSLGLYAAVVQLSWSWAAWWRAACDMEKGFCGWLCSKLGLE 263

  Fly   392 DCSPYEVVILTD 403
            |||||.:|.|.:
  Rat   264 DCSPYSIVELLE 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4596	NP_650031.1	TMEM169	275..405	CDD:464471	59/129 (46%)
Tmem169	NP_001103044.1	TMEM169	147..277	CDD:464471	59/129 (46%)