DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fdh and AT1G32780

DIOPT Version :9

Sequence 1:	NP_524310.1	Gene:	Fdh / 41311	FlyBaseID:	FBgn0011768	Length:	379	Species:	Drosophila melanogaster
Sequence 2:	NP_564409.1	Gene:	AT1G32780 / 840172	AraportID:	AT1G32780	Length:	394	Species:	Arabidopsis thaliana

Alignment Length:	389	Identity:	173/389 - (44%)
Similarity:	248/389 - (63%)	Gaps:	13/389 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSATEGKVITCKAAVAWEAKKPLVIEDIEVAPPKAHEVRIKITATGVCHTDAFTLSGA-DPEGLF 64
            |:.|:||||||||||.|..|.||||::|.|.||:..|||:||..:.:||||....:|. :.|..|
plant     1 MAETQGKVITCKAAVVWGPKVPLVIQEICVDPPQKMEVRVKILYSSICHTDLGCWNGTNEAERAF 65

  Fly    65 PVVLGHEGAGIVESVGEGVTNFKAGDHVIALYIPQCNECKFCKSGKTNLCQKIRLTQGAGVM-PE 128
            |.:||||..||||||||||.:.|.||:||..:..:|.|||.||..::|||::..:.....|| .:
plant    66 PRILGHEAVGIVESVGEGVKDVKEGDYVIPTFNGECGECKVCKREESNLCERYHVDPMKRVMVND 130

  Fly   129 GTSRL---------SCKGQQLFHFMGTSTFAEYTVVADISLTKINEKAPLEKVCLLGCGISTGYG 184
            |.:|.         |.:.|.::||:.||||.||||:....:.||:..:||:::.||.||:|||.|
plant   131 GGTRFSTTINKDGGSSQSQPIYHFLNTSTFTEYTVLDSACVVKIDPNSPLKQMSLLSCGVSTGVG 195

  Fly   185 AALNTAKVEAGSTCAVWGLGAVGLAVGLGCKKAGAGKIYGIDINPDKFELAKKFGFTDFVNPKDV 249
            ||.|.|.|:.|.:.||:|||:|||||..|.:..||.:|.|:|.|..|||..|..|.|||:||||:
plant   196 AAWNIANVKEGKSTAVFGLGSVGLAVAEGARARGASRIIGVDANASKFEKGKLMGVTDFINPKDL 260

  Fly   250 ADKGSIQNYLIDLTDGGFDYTFECIGNVNTMRSALEATHKGWGTSVVIGVAGAGQEISTRPFQLV 314
            ..  .:...:.::|.||.||:|||.|||:.:|.|..:||.|||::|::|:....:.:...|.:|.
plant   261 TK--PVHQMIREITGGGVDYSFECTGNVDVLREAFLSTHVGWGSTVLVGIYPTPRTLPLHPMELF 323

  Fly   315 VGRVWKGSAFGGWRSVSDVPKLVEDYLKKDLLVDEFITHELPLSQINEAFDLMHKGESIRSIIK 378
            .||...||.|||::..|.:|...:..:|..:.::.|||:|||..:||:||.|:..|:|:|.|::
plant   324 DGRRITGSVFGGFKPKSQLPNFAQQCMKGVVKLEPFITNELPFEKINDAFQLLRDGKSLRCILQ 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fdh	NP_524310.1	FrmA	9..379	CDD:223990	168/381 (44%)
Fdh	NP_524310.1	alcohol_DH_class_III	9..378	CDD:176260	168/379 (44%)
AT1G32780	NP_564409.1	PLN02740	1..388	CDD:178341	173/389 (44%)
AT1G32780	NP_564409.1	alcohol_DH_plants	9..387	CDD:176261	168/379 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1062
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D664798at2759
OrthoFinder	1	1.000	-	-		FOG0000360
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43880
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.880