Protein Alignment Fdh and Adh6

DIOPT Version :10

• Sequence 1: NP_524310.1
• Gene: Fdh / 41311
• FlyBaseID: FBgn0011768
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: XP_063138044.1
• Gene: Adh6 / 310903
• RGDID: 1306313
• Length: 413
• Species: Rattus norvegicus
• Alignment Length: 378
• Identity: 190/378 - (50%)
• Similarity: 252/378 - (66%)
• Gaps: 4/378 - (1%)

  Fly     1 MSATEGKVITCKAAVAWEAKKPLVIEDIEVAPPKAHEVRIKITATGVCHTDAFTLSGADPEGLFP 65
            |...|..||.|||.|.|:...||.||:||||||||.|||||:.|||||.||...|...:.....|
  Rat    37 MIKMEPGVIRCKATVLWKPGAPLAIEEIEVAPPKAKEVRIKMVATGVCGTDIKHLDTQELSKFCP 101

  Fly    66 VVLGHEGAGIVESVGEGVTNFKAGDHVIALYIPQCNECKFCKSGKTNLCQKIRLTQGAGVMPEGT 130
            :::||||.||||||||||::.:.||.||.|.||||.|||.|.:.|.|:|.:|||:: ..:..|||
  Rat   102 MIMGHEGVGIVESVGEGVSSVRTGDKVILLCIPQCGECKTCLNSKNNICTEIRLSK-THLASEGT 165

  Fly   131 SRLSCKGQQLFHFMGTSTFAEYTVVADISLTKINEKAPLEKVCLLGCGISTGYGAALNTAKVEAG 195
            ||::|||:.:..::...:|:||||:.:||:.||:|.|||||||::|||.:||||||:|:|||..|
  Rat   166 SRITCKGKLVHQYIALGSFSEYTVLKEISVAKIDEGAPLEKVCIIGCGFATGYGAAINSAKVTPG 230

  Fly   196 STCAVWGLGAVGLAVGLGCKKAGAGKIYGIDINPDKFELAKKFGFTDFVNPKDVADKGSIQNYLI 260
            |||||:|||.|||:|.:|||.|||.:|..:|||.|:|..||..|.||.|:|:|.  :..|:..|.
  Rat   231 STCAVFGLGGVGLSVIIGCKAAGAARIIAVDINKDRFAKAKTVGATDCVDPRDF--EKPIEEVLS 293

  Fly   261 DLTDGGFDYTFECIGNVNTMRSALEATHKGWGTSVVIG-VAGAGQEISTRPFQLVVGRVWKGSAF 324
            |:.|||.|:.||..||...:.:||.:.||..|..|.:| :|.....:|.|......||:.|||..
  Rat   294 DMIDGGVDFCFEVTGNTEAVGAALGSCHKDHGVCVTVGALASFTSTLSIRSHLFFSGRILKGSIL 358

  Fly   325 GGWRSVSDVPKLVEDYLKKDLLVDEFITHELPLSQINEAFDLMHKGESIRSII 377
            |||::..::||||.||:.|...:|..|||.|.||:.|||..||..|:.||.::
  Rat   359 GGWKTKEEIPKLVSDYMAKKFNIDPLITHTLTLSEANEAVQLMKSGQCIRCVL 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fdh	NP_524310.1	alcohol_DH_class_III	9..378	CDD:176260	187/370 (51%)
Adh6	XP_063138044.1	None