DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fdh and SPBC1539.07c

DIOPT Version :9

Sequence 1:	NP_524310.1	Gene:	Fdh / 41311	FlyBaseID:	FBgn0011768	Length:	379	Species:	Drosophila melanogaster
Sequence 2:	NP_596821.1	Gene:	SPBC1539.07c / 2540073	PomBaseID:	SPBC1539.07c	Length:	378	Species:	Schizosaccharomyces pombe

Alignment Length:	373	Identity:	227/373 - (60%)
Similarity:	280/373 - (75%)	Gaps:	3/373 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 EGKVITCKAAVAWEAKKPLVIEDIEVAPPKAHEVRIKITATGVCHTDAFTLSGADPEGLFPVVLG 69
            |||.|||||||||.||:||.||||:||||||||||:|:..:.||||||:||||.||||.||:|||
pombe     4 EGKTITCKAAVAWGAKEPLSIEDIQVAPPKAHEVRVKVDWSAVCHTDAYTLSGVDPEGAFPIVLG 68

  Fly    70 HEGAGIVESVGEGVTNFKAGDHVIALYIPQCNECKFCKSGKTNLCQKIRLTQGAGVMPEGTSRLS 134
            |||||||||:||||.|.:.|||||.||.|:|.|||||:|||||||.|||.|||.|:||:||||.|
pombe    69 HEGAGIVESIGEGVINVRPGDHVILLYTPECKECKFCRSGKTNLCSKIRETQGRGLMPDGTSRFS 133

  Fly   135 CKGQQLFHFMGTSTFAEYTVVADISLTKINEKAPLEKVCLLGCGISTGYGAALNTAKVEAGSTCA 199
            |:.:.|.|:||.|:|::|||||||||..|:..|||..:||||||::||:||..::||||:|||.|
pombe   134 CRDKTLLHYMGCSSFSQYTVVADISLVAISHSAPLRSICLLGCGVTTGFGAVTHSAKVESGSTVA 198

  Fly   200 VWGLGAVGLAVGLGCKKAGAGKIYGIDINPDKFELAKKFGFTDFVNPKDVADKGSIQNYLIDLTD 264
            |.|.|.||||...|...|||.:|..||||.||...|||||.|||::...|.|   :..|:||:||
pombe   199 VVGCGCVGLAAMQGAVAAGASRIIAIDINADKEVYAKKFGATDFIDSSKVKD---LVQYVIDVTD 260

  Fly   265 GGFDYTFECIGNVNTMRSALEATHKGWGTSVVIGVAGAGQEISTRPFQLVVGRVWKGSAFGGWRS 329
            ||.||.|:|.|||..|:..|:..|||||...|||||.||:.:..|||.:|.||...||||||.:.
pombe   261 GGVDYAFDCTGNVTVMQQELQFCHKGWGKLCVIGVAAAGKTLDFRPFLVVTGRQVLGSAFGGVKG 325

  Fly   330 VSDVPKLVEDYLKKDLLVDEFITHELPLSQINEAFDLMHKGESIRSII 377
            .|::|..|::|::....|||:||:|.||..||:|||.||:|:.||.::
pombe   326 RSELPNFVDEYMQGHFKVDEYITNEEPLKNINKAFDHMHEGKCIRCVV 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fdh	NP_524310.1	FrmA	9..379	CDD:223990	224/369 (61%)
Fdh	NP_524310.1	alcohol_DH_class_III	9..378	CDD:176260	224/369 (61%)
SPBC1539.07c	NP_596821.1	FrmA	8..375	CDD:223990	224/369 (61%)
SPBC1539.07c	NP_596821.1	alcohol_DH_class_III	8..374	CDD:176260	224/369 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	59	1.000	Domainoid score	I3044
eggNOG	1	0.900	-	-		E1_COG1062
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG63142
OrthoFinder	1	1.000	-	-		FOG0000360
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100471
Panther	1	1.100	-	-	O	PTHR43880
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1695
TreeFam	1	0.960	-	-
	10	9.780