Protein Alignment Fdh and Adh1c

DIOPT Version :10

• Sequence 1: NP_524310.1
• Gene: Fdh / 41311
• FlyBaseID: FBgn0011768
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_062159.3
• Gene: Adh1c / 24172
• RGDID: 2044
• Length: 376
• Species: Rattus norvegicus
• Alignment Length: 381
• Identity: 213/381 - (55%)
• Similarity: 273/381 - (71%)
• Gaps: 10/381 - (2%)

  Fly     3 ATEGKVITCKAAVAWEAKKPLVIEDIEVAPPKAHEVRIKITATGVCHTDAFTLSGADPEGLF--- 64
            :|.||||.|||||.||..||..|||||||||||||||||:.|||||.:|...:||:    ||
  Rat     2 STAGKVIKCKAAVLWEPHKPFTIEDIEVAPPKAHEVRIKMVATGVCRSDDHAVSGS----LFTPL 62

  Fly    65 PVVLGHEGAGIVESVGEGVTNFKAGDHVIALYIPQCNECKFCKSGKTNL-CQKIRLTQGAGVMPE 128
            |.||||||||||||:|||||..|.||.||.|:.|||.:|:.||..::|| ||...|||..|.:.:
  Rat    63 PAVLGHEGAGIVESIGEGVTCVKPGDKVIPLFSPQCGKCRICKHPESNLCCQTKNLTQPKGALLD 127

  Fly   129 GTSRLSCKGQQLFHFMGTSTFAEYTVVADISLTKINEKAPLEKVCLLGCGISTGYGAALNTAKVE 193
            ||||.||:|:.:.||:.||||::||||.||::.||:..|||:||||:|||.|||||:|:..|||.
  Rat   128 GTSRFSCRGKPIHHFISTSTFSQYTVVDDIAVAKIDAAAPLDKVCLIGCGFSTGYGSAVQVAKVT 192

  Fly   194 AGSTCAVWGLGAVGLAVGLGCKKAGAGKIYGIDINPDKFELAKKFGFTDFVNPKDVADKGSIQNY 258
            .||||||:|||.|||:|.:|||.|||.||..:|||.|||..||:.|.||.:||:|...  .||..
  Rat   193 PGSTCAVFGLGGVGLSVVIGCKTAGAAKIIAVDINKDKFAKAKELGATDCINPQDYTK--PIQEV 255

  Fly   259 LIDLTDGGFDYTFECIGNVNTMRSALEATHKGWGTSVVIGVAGAGQEISTRPFQLVVGRVWKGSA 323
            |.::||||.|::||.||.::||.|||.:.|...|.||::||..:.|.:|..|..|::||.|||:.
  Rat   256 LQEMTDGGVDFSFEVIGRLDTMTSALLSCHSACGVSVIVGVPPSAQSLSVNPMSLLLGRTWKGAI 320

  Fly   324 FGGWRSVSDVPKLVEDYLKKDLLVDEFITHELPLSQINEAFDLMHKGESIRSIIKY 379
            |||::|...|||||.|::.|...::..|||.||..:|||||||:..|:|||:::.:
  Rat   321 FGGFKSKDAVPKLVADFMAKKFPLEPLITHVLPFEKINEAFDLLRAGKSIRTVLTF 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fdh	NP_524310.1	alcohol_DH_class_III	9..378	CDD:176260	209/372 (56%)
Adh1c	NP_062159.3	alcohol_DH_class_I_II_IV	3..376	CDD:176259	213/378 (56%)