Protein Alignment Fdh and ADH7

DIOPT Version :10

• Sequence 1: NP_524310.1
• Gene: Fdh / 41311
• FlyBaseID: FBgn0011768
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_001159976.1
• Gene: ADH7 / 131
• HGNCID: 256
• Length: 394
• Species: Homo sapiens
• Alignment Length: 377
• Identity: 197/377 - (52%)
• Similarity: 258/377 - (68%)
• Gaps: 4/377 - (1%)

  Fly     3 ATEGKVITCKAAVAWEAKKPLVIEDIEVAPPKAHEVRIKITATGVCHTDAFTLSGADPEGLFPVV 67
            :.|..||.|||||.||.|:|..||:|||||||..||||||.|||:|.||...:.|. ....|||:
Human    22 SVEAGVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGT-MVSKFPVI 85

  Fly    68 LGHEGAGIVESVGEGVTNFKAGDHVIALYIPQCNECKFCKSGKTNLCQKIRLTQGAGVMPEGTSR 132
            :|||..|||||:|||||..|.||.||.|::|||.||..|::...|||.:..:| |.||:.:||:|
Human    86 VGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDIT-GRGVLADGTTR 149

  Fly   133 LSCKGQQLFHFMGTSTFAEYTVVADISLTKINEKAPLEKVCLLGCGISTGYGAALNTAKVEAGST 197
            .:|||:.:.|||.||||.|||||.:.|:.||::.||.|||||:|||.|||||||:.|.||:.|||
Human   150 FTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGST 214

  Fly   198 CAVWGLGAVGLAVGLGCKKAGAGKIYGIDINPDKFELAKKFGFTDFVNPKDVADKGSIQNYLIDL 262
            |.|:|||.|||:|.:|||.|||.:|.|||:|.||||.|...|.|:.::|||  ....|...|.::
Human   215 CVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKD--STKPISEVLSEM 277

  Fly   263 TDGGFDYTFECIGNVNTMRSALEATHKGWGTSVVIGVAGAGQEISTRPFQLVVGRVWKGSAFGGW 327
            |.....||||.||::.||..||.:.|..:|||||:||..:.:.::..|..|..||.|||..|||.
Human   278 TGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGL 342

  Fly   328 RSVSDVPKLVEDYLKKDLLVDEFITHELPLSQINEAFDLMHKGESIRSIIKY 379
            :|..||||||.::|.|...:|:.|||.||..:|:|.|:|::.|:|||:::.:
Human   343 KSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSIRTVLTF 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fdh	NP_524310.1	alcohol_DH_class_III	9..378	CDD:176260	195/368 (53%)
ADH7	NP_001159976.1	alcohol_DH_class_I_II_IV	27..394	CDD:176259	196/370 (53%)