Protein Alignment Fdh and Adh7

DIOPT Version :9

• Sequence 1: NP_524310.1
• Gene: Fdh / 41311
• FlyBaseID: FBgn0011768
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_033756.2
• Gene: Adh7 / 11529
• MGIID: 87926
• Length: 374
• Species: Mus musculus
• Alignment Length: 376
• Identity: 197/376 - (52%)
• Similarity: 257/376 - (68%)
• Gaps: 4/376 - (1%)

  Fly     4 TEGKVITCKAAVAWEAKKPLVIEDIEVAPPKAHEVRIKITATGVCHTDAFTLSGADPEGLFPVVL 68
            |.||||.|||||.|...:|..||:||||||||.|||:||.|||:|.||...:.|: ....|||::
Mouse     3 TAGKVIKCKAAVLWGVNQPFSIEEIEVAPPKAKEVRVKILATGICRTDDHIIKGS-MVSKFPVIV 66

  Fly    69 GHEGAGIVESVGEGVTNFKAGDHVIALYIPQCNECKFCKSGKTNLCQKIRLTQGAGVMPEGTSRL 133
            |||..|:|||||||||..:.||.||.|::|||.||..|.:.:.|||.:..|| |.||:.:||:|.
Mouse    67 GHEAVGVVESVGEGVTTVRPGDKVIPLFLPQCRECNACLNPEGNLCIRSDLT-GRGVLADGTTRF 130

  Fly   134 SCKGQQLFHFMGTSTFAEYTVVADISLTKINEKAPLEKVCLLGCGISTGYGAALNTAKVEAGSTC 198
            :|||:.:.|||.||||.||||:.:.|:.|::..||.||.||:|||.|||||||:.||||..||||
Mouse   131 TCKGKPVQHFMNTSTFTEYTVLDESSVAKVDGAAPPEKACLIGCGFSTGYGAAVKTAKVTPGSTC 195

  Fly   199 AVWGLGAVGLAVGLGCKKAGAGKIYGIDINPDKFELAKKFGFTDFVNPKDVADKGSIQNYLIDLT 263
            .|:|||.|||:|.:|||.|||.:|.|||||.|||:.|...|.|:.::|||  ....|...|.|:|
Mouse   196 VVFGLGGVGLSVIMGCKAAGASRIIGIDINKDKFQKALAVGATECISPKD--STKPISEVLSDMT 258

  Fly   264 DGGFDYTFECIGNVNTMRSALEATHKGWGTSVVIGVAGAGQEISTRPFQLVVGRVWKGSAFGGWR 328
            .....||||.||.:.||..||.:.|..:|||||:|...:.:.::..|..|..||.|||..||||:
Mouse   259 GNTIQYTFEVIGRLETMVDALSSCHMNYGTSVVVGAPPSAKMLTYDPMLLFTGRTWKGCVFGGWK 323

  Fly   329 SVSDVPKLVEDYLKKDLLVDEFITHELPLSQINEAFDLMHKGESIRSIIKY 379
            |..||||||.::|:|...:|:.|||.||.:.|||.|:|::.|:|||:::.:
Mouse   324 SRDDVPKLVTEFLEKKFDLDQLITHTLPFNNINEGFELLYSGKSIRTVLTF 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fdh	NP_524310.1	FrmA	9..379	CDD:223990	193/369 (52%)
		alcohol_DH_class_III	9..378	CDD:176260	193/368 (52%)
Adh7	NP_033756.2	alcohol_DH_class_I_II_IV	3..374	CDD:176259	197/374 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	54	1.000	Domainoid score	I11186
eggNOG	1	0.900	-	-		E1_COG1062
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D324108at33208
OrthoFinder	1	1.000	-	-		FOG0000360
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100471
Panther	1	1.100	-	-	O	PTHR43880
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.780