Protein Alignment Fdh and Adh7

DIOPT Version :10

• Sequence 1: NP_524310.1
• Gene: Fdh / 41311
• FlyBaseID: FBgn0011768
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_033756.2
• Gene: Adh7 / 11529
• MGIID: 87926
• Length: 374
• Species: Mus musculus
• Alignment Length: 376
• Identity: 197/376 - (52%)
• Similarity: 257/376 - (68%)
• Gaps: 4/376 - (1%)

  Fly     4 TEGKVITCKAAVAWEAKKPLVIEDIEVAPPKAHEVRIKITATGVCHTDAFTLSGADPEGLFPVVL 68
            |.||||.|||||.|...:|..||:||||||||.|||:||.|||:|.||...:.|: ....|||::
Mouse     3 TAGKVIKCKAAVLWGVNQPFSIEEIEVAPPKAKEVRVKILATGICRTDDHIIKGS-MVSKFPVIV 66

  Fly    69 GHEGAGIVESVGEGVTNFKAGDHVIALYIPQCNECKFCKSGKTNLCQKIRLTQGAGVMPEGTSRL 133
            |||..|:|||||||||..:.||.||.|::|||.||..|.:.:.|||.:..|| |.||:.:||:|.
Mouse    67 GHEAVGVVESVGEGVTTVRPGDKVIPLFLPQCRECNACLNPEGNLCIRSDLT-GRGVLADGTTRF 130

  Fly   134 SCKGQQLFHFMGTSTFAEYTVVADISLTKINEKAPLEKVCLLGCGISTGYGAALNTAKVEAGSTC 198
            :|||:.:.|||.||||.||||:.:.|:.|::..||.||.||:|||.|||||||:.||||..||||
Mouse   131 TCKGKPVQHFMNTSTFTEYTVLDESSVAKVDGAAPPEKACLIGCGFSTGYGAAVKTAKVTPGSTC 195

  Fly   199 AVWGLGAVGLAVGLGCKKAGAGKIYGIDINPDKFELAKKFGFTDFVNPKDVADKGSIQNYLIDLT 263
            .|:|||.|||:|.:|||.|||.:|.|||||.|||:.|...|.|:.::|||  ....|...|.|:|
Mouse   196 VVFGLGGVGLSVIMGCKAAGASRIIGIDINKDKFQKALAVGATECISPKD--STKPISEVLSDMT 258

  Fly   264 DGGFDYTFECIGNVNTMRSALEATHKGWGTSVVIGVAGAGQEISTRPFQLVVGRVWKGSAFGGWR 328
            .....||||.||.:.||..||.:.|..:|||||:|...:.:.::..|..|..||.|||..||||:
Mouse   259 GNTIQYTFEVIGRLETMVDALSSCHMNYGTSVVVGAPPSAKMLTYDPMLLFTGRTWKGCVFGGWK 323

  Fly   329 SVSDVPKLVEDYLKKDLLVDEFITHELPLSQINEAFDLMHKGESIRSIIKY 379
            |..||||||.::|:|...:|:.|||.||.:.|||.|:|::.|:|||:::.:
Mouse   324 SRDDVPKLVTEFLEKKFDLDQLITHTLPFNNINEGFELLYSGKSIRTVLTF 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fdh	NP_524310.1	alcohol_DH_class_III	9..378	CDD:176260	193/368 (52%)
Adh7	NP_033756.2	alcohol_DH_class_I_II_IV	3..374	CDD:176259	197/374 (53%)